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A 78-year-old man fell from a ladder and suffered a right distal tibial fracture On the seventh day after injury, A 78-year-old man developed a low-grade fever and was isolated in a private room Polymerase chain reaction for COVID-19 was positive (day 4 from the day of saliva sampling) On day 5, A 78-year-old man required 1 liter per minute of oxygen and dexamethasone therapy was initiated On day 6, A 78-year-old man's D-dimer level was 25 0 mu g/mL, and continuous infusion of heparin was initiated From day 7, A 78-year-old man was administered remdesivir On day 9, A 78-year-old man's oxygenation suddenly showed a remarkable deterioration A 78-year-old man received a tentative diagnosis of COVID-19-induced pneumonia accompanied by severe acute respiratory distress syndrome (ARDS) and underwent urgent tracheal intubation and mechanical ventilation A 78-year-old man also received intravenous immunoglobulin (IVIG) and was also administered glycyrrhizin his oxygenation gradually improved and extubation was performed on day 15 Following rehabilitation, A 78-year-old man did not require oxygen on day 19 On day 20, A 78-year-old man's D-dimer level was found to be increased and enhanced computed tomography revealed pulmonary embolism A 78-year-old man was prescribed a direct oral anticoagulant On day 28 A 78-year-old man was transferred to a general ward for rehabilitation These unspecific antiviral therapies and immune modulation therapy may be useful treatments for the main cause of severe acute respiratory distress syndrome (ARDS), which may explain the favorable outcome that was obtained in the present case
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