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Purpose: To determine the preference of patients undergoing bilateral LASIK for either the dexamethasone intracanalicular insert or topical prednisolone acetate for control of postoperative symptoms and ocular surface signs Methods: In this randomized clinical trial, one eye was randomized to receive the dexamethasone intracanalicular insert or topical prednisolone acetate topical prednisolone acetate 1% four times daily for one week and 2 times daily for a second week;the fellow eye received the alternate therapy One month postoperatively, patient preference for the dexamethasone intracanalicular insert or topical prednisolone acetate was assessed using an adapted COMTOL questionnaire Ocular comfort was assessed using the SPEED questionnaire Corneal staining and uncorrected distance visual acuity (UDVA) were also assessed Results: Twenty patients participated At Month 1, 80% of patients preferred the dexamethasone intracanalicular insert, 10% preferred topical prednisolone acetate, and 10% expressed no preference (p 0 001) SPEED scores measuring ocular comfort/discomfort related to dry eye symptoms were similar between groups (p=0 72), and both the incidence of patient-reported ocular dryness and the corneal staining scores were similar between groups Both groups attained the same final uncorrected distance visual acuity (UDVA) Conclusion: Patients undergoing elective bilateral femtosecond LASIK surgery overwhelmingly (by an 8-to-1 margin) preferred the dexamethasone intracanalicular insert to topical prednisolone acetate for postoperative treatment the dexamethasone intracanalicular insert produced comparable ocular comfort, corneal staining, and visual acuity outcomes to topical prednisolone acetate the dexamethasone intracanalicular insert is an appropriate means of postoperative symptom control in this quality of life-conscious population
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visual acuity outcomes to topical prednisolone acetate the dexamethasone intracanalicular insert is an appropriate means of postoperative symptom control in this quality of life - conscious population
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