@prefix dc1: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAOmjLZDzPq1WYE5K6mHvTZBfpmxUle_QCHbhtd5WzQCw> .
@prefix sub: <http://purl.org/np/RAOmjLZDzPq1WYE5K6mHvTZBfpmxUle_QCHbhtd5WzQCw#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_8986> bl:category bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_8986> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://identifiers.org/drugbank:DB01576> ;
    a rdf:Statement ;
    rdfs:label "dextroamphetamine sulfate extended release capsules are indicated in narcolepsy attention deficit disorder with hyperactivity as an integral part of a total treatment program that typically includes other measures psychological educational social for patients ages 6 years to 16 years with this syndrome a diagnosis of attention deficit hyperactivity disorder adhd dsm iv implies the presence of the hyperactive impulsive or inattentive symptoms that caused impairment and were present before age 7 years the symptoms must cause clinically significant impairment e g in social academic or occupational functioning and be present in 2 or more settings e g school or work and at home the symptoms must not be better accounted for by another mental disorder for the inattentive type at least 6 of the following symptoms must have persisted for at least 6 months lack of attention to details careless mistakes lack of sustained attention poor listener failure to follow through on tasks poor organization avoids tasks requiring sustained mental effort loses things easily distracted forgetful for the hyperactive impulsive type at least 6 of the following symptoms must have persisted for at least 6 months fidgeting squirming leaving seat inappropriate running climbing difficulty with quiet activities on the go excessive talking blurting answers can t wait turn intrusive the combined type requires both inattentive and hyperactive impulsive criteria to be met special diagnostic considerations specific etiology of this syndrome is unknown and there is no single diagnostic test adequate diagnosis requires the use of medical and special psychological educational and social resources learning may or may not be impaired the diagnosis must be based upon a complete history and evaluation of the patient and not solely on the presences of the required number of dsm iv characteristics need for comprehensive treatment program dextroamphetamine sulfate extended release capsules are indicated as an integral part of a total treatment program for adhd that may include other measures psychological educational social for patients with this syndrome drug treatment may not be indicated for all patients with this syndrome stimulants are not intended for use in patients who exhibit symptoms secondary to environmental factors and or other primary psychiatric disorders including psychosis appropriate educational placement is essential and psychosocial intervention is often helpful when remedial measures alone are insufficient the decision to prescribe stimulant medication will depend upon the physician s assessment of the chronicity and severity of the patient s symptoms" ;
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:relation schema:TreatmentIndication .
  <https://identifiers.org/drugbank:DB01576> bl:category bl:Drug .
}
sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}
sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA" ;
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    npx:hasSignatureTarget this: .
  this: dc1:created "2021-06-13T14:21:58.382+02:00"^^xsd:dateTime ;
    dc1:creator orcid:0000-0002-1468-3557 ;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM> ;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM> ;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs> .
}