@prefix orcid: <https://orcid.org/> .
@prefix this: <http://purl.org/np/RAPrl16L80CIV3rcdxFwwW4hZVuMKrbnrj_vPFgg9Dzy0> .
@prefix sub: <http://purl.org/np/RAPrl16L80CIV3rcdxFwwW4hZVuMKrbnrj_vPFgg9Dzy0#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix ns2: <http://twoc-nlp-database-server-1:8555/solr/predicates/select?q=> .
@prefix ns1: <https://uts.nlm.nih.gov/uts/umls/concept/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix ns3: <http://twoc-nlp-database-server-1:8555/solr/triples/select?q=> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubInfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:assertion prov:wasGeneratedBy "S&T TWOC project version 1" .
  sub:version prov:value 1 .
  rdf:object ns1:C0086582 "male" ;
    ns1:C0439234 "years" ;
    ns1:C1706180 "male" ;
    ns1:C1706428 "male" ;
    ns1:C1706429 "male" .
  rdf:predicate ns2:TRIPLE_UID:39u835ce-TRIPLE-ABSTRACT-17 "be" .
  rdf:subject ns1:C0011777 "dexamethasone" .
  rdfs:Triple-UID ns3:TRIPLE_UID:39u835ce-TRIPLE-ABSTRACT-17 "39u835ce-TRIPLE-ABSTRACT-17" .
  rdfs:sentence rdfs:label "A clinical interpretation of the Randomized Evaluation of COVID-19 Therapy (RECOVERY) study was performed to provide a useful tool to understand whether, when, and to whom dexamethasone should be administered during hospitalization for COVID-19 A post hoc analysis of data published in the preliminary report of the Randomized Evaluation of COVID-19 Therapy (RECOVERY) study was performed to calculate the person-based number needed to treat (NNT) and number needed to harm (NNH) of 6 mg dexamethasone once daily for up to 10 days vs usual care with respect to mortality At day 28, the NNT of dexamethasone vs usual care was 36 0 (95%CI 24 9–65 1, p &lt;0 05) in all patients, 8 3 (95%CI 6 0–13 1, p &lt;0 05) in patients receiving invasive mechanical ventilation, and 34 6 (95%CI 22 1–79 0, p &lt;0 05) in patients receiving oxygen only (with or without noninvasive ventilation) dexamethasone increased mortality compared with usual care in patients not requiring oxygen supplementation, leading to a NNH value of 26 7 (95%CI 18 1–50 9, p &lt;0 05) NNT of dexamethasone vs usual care was 17 3 (95%CI 14 9–20 6) in subjects &lt;70 years, 27 0 (95%CI 18 5–49 8) in men, and 16 2 (95%CI 13 2–20 8) in patients in which the onset of symptoms was &gt;7 days dexamethasone is effective in male subjects &lt;70 years that require invasive mechanical ventilation experiencing symptoms from &gt;7 days and those patients receiving oxygen without invasive mechanical ventilation;it should be avoided in patients not requiring respiratory support" .
  rdfs:triple rdfs:label "dexamethasone is in male subjects & lt;70 years" .
}
sub:provenance {
   sub:assertion prov:generatedAtTime "2021-07-25T21:47:40.361459"^^xsd:dateTime .
}
sub:pubInfo {
   sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCSLeezU8JYlBsrgXOGXX4fxOq4oydsMzMK1CN0Rez2OEd2IYk18R4DetcZXwGhN3Pil7qcgNkiGvTirJXIo8zHl7jVehs19EdYtrttCKEaXRzWIr4LuCrfGedkvonEMWqR8e1GdQsLgEEyM50BD6Qw+srQt9ozcqf/9wG2MAMX9QIDAQAB" ;
    npx:hasSignature "cNcX3RSgSXaBGY4tnz3wWzdnOI6Whvgiq7oGY0cuhGAof+zRK6lG0i4+vrhOn9sbGm95z9Hv41xK5nclF580+ol/vdW00gaf8arkKF2MTF1FhBxkgOZl2PG0f0o0hPpDCdxuQc8KCPoKFjU8YYIjrWWygbxXGe2zLzE7imp13YM=" ;
    npx:hasSignatureTarget this: .
  this: prov:generatedAtTime "2021-07-25T21:47:40.361459"^^xsd:dateTime ;
    prov:wasAttributedTo orcid:0000-0002-8954-0470 .
}