@prefix biolink: <
https://w3id.org/biolink/vocab/
> .
@prefix ns1: <
https://w3id.org/np/o/ntemplate/
> .
@prefix this: <
http://purl.org/np/RASrQxw3symNpsQWZ1tQhjE12x7WiOB4ymboKpwqt9KrI
> .
@prefix sub: <
http://purl.org/np/RASrQxw3symNpsQWZ1tQhjE12x7WiOB4ymboKpwqt9KrI#
> .
@prefix schema: <
https://schema.org/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/DOID_409
>
biolink:category
biolink:Disease
.
sub:association
rdf:object
<
http://purl.obolibrary.org/obo/DOID_409
> ;
rdf:predicate
biolink:treats
;
rdf:subject
<
https://identifiers.org/drugbank:DB00744
> ;
a
rdf:Statement
;
rdfs:label
"\"The use of Zileuton Extended-Release Tablets is contraindicated in patients with: Active liver disease or persistent hepatic function enzyme elevations greater than or equal to 3 times the upper limit of normal (>=3xULN) [see Warnings and Precautions (5) Use in Specific Populations (8.7) A history of allergic reaction to zileuton or any of the ingredients of Zileuton Extended Release Tablets (e.g., rash, eosinophilia, etc.). Active liver disease or persistent hepatic function enzyme elevations >=3 times the upper limit of normal. ( 4 5.1 History of allergic reaction to Zileuton or any of the ingredients of Zileuton Extended-Release Tablets. ( 4\"" ;
biolink:provided_by
<
https://w3id.org/um/NeuroDKG
> ;
biolink:relation
schema:MedicalContraindication
.
<
https://identifiers.org/drugbank:DB00744
>
biolink:category
biolink:Drug
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-1468-3557
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB" ;
npx:hasSignature
"X7+BvuEhn6t7Pam8pE9RWoXjVgYaYfbQ9BDFItywvs/blGatCdU5TMO9gR4W+6o73frnCoSPDSj4KmrVnMjtAOaEmK8lPjPe3BHj1eaTtQmvOxVJZ6QT++lEmuM4lqdfw/93RRcLHFIszw7g/1uIcG5xWupEHoJceKRDpFv7dzg=" ;
npx:hasSignatureTarget
this:
.
this:
dct:created
"2021-08-25T13:58:13.360+02:00"^^
xsd:dateTime
;
dct:creator
orcid:0000-0002-1468-3557
;
ns1:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
ns1:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
ns1:wasCreatedFromTemplate
<
http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY
> .
}