sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_5408> bl:category bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_5408> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://identifiers.org/drugbank:DB00017> ;
    a rdf:Statement ;
    rdfs:label "miacalcin synthetic injection is a calcitonin indicated for the following conditions 1 1 1 2 1 3 limitations of use 1 4 5 3 miacalcin injection is indicated for the treatment of symptomatic paget s disease of bone in patients with moderate to severe disease characterized by polyostotic involvement with elevated serum alkaline phosphatase and urinary hydroxyproline excretion there is no evidence that the prophylactic use of calcitonin salmon is beneficial in asymptomatic patients miacalcin injection should be used only in patients who do not respond to alternative treatments or for whom such treatments are not suitable e g patients for whom other therapies are contraindicated or for patients who are intolerant or unwilling to use other therapies miacalcin injection is indicated for the early treatment of hypercalcemic emergencies along with other appropriate agents when a rapid decrease in serum calcium is required until more specific treatment of the underlying disease can be accomplished it may also be added to existing therapeutic regimens for hypercalcemia such as intravenous fluids and furosemide oral phosphate or corticosteroids or other agents miacalcin injection is indicated for the treatment of postmenopausal osteoporosis in women greater than 5 years postmenopause the evidence of efficacy for calcitonin salmon injection is based on increases in total body calcium observed in clinical trials fracture reduction efficacy has not been demonstrated miacalcin injection should be reserved for patients for whom alternative treatments are not suitable e g patients for whom other therapies are contraindicated or for patients who are intolerant or unwilling to use other therapies due to the possible association between malignancy and calcitonin salmon use the need for continued therapy should be re evaluated on a periodic basis see warnings and precautions 5 3" ;
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:relation nkg:SymptomaticReliefIndication .
  <https://identifiers.org/drugbank:DB00017> bl:category bl:Drug .
}