@prefix dcterms: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://purl.org/np/RAaTX5aHox7tzzPG9AMdX1SYvVVLT0O0UMTXQNgpHaWyA
> .
@prefix sub: <
http://purl.org/np/RAaTX5aHox7tzzPG9AMdX1SYvVVLT0O0UMTXQNgpHaWyA#
> .
@prefix schema: <
https://schema.org/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix nt: <
https://w3id.org/np/o/ntemplate/
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix nkg: <
https://w3id.org/neurodkg/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/DOID_1094
>
schema:possibleTreatment
sub:medtherapy
;
schema:signOrSymptom
<
http://purl.bioontology.org/ontology/MEDDRA/10013486
> , <
http://purl.bioontology.org/ontology/MEDDRA/10014555
> , <
http://purl.bioontology.org/ontology/OMIM/MTHU000554
> , <
https://identifiers.org/HP:0000736
> , <
https://identifiers.org/HP:0100710
> .
sub:medtherapy
prov:wasDerivedFrom
sub:quote
;
schema:drug
<
http://identifiers.org/drugbank/DB00422
> ;
schema:targetPopulation
sub:targetpop
;
nkg:indicationType
nkg:AdjunctiveTherapy
.
sub:quote
prov:value
"Methylphenidate Hydrochloride is indicated as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate-to-severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity" ;
prov:wasQuotedFrom
<
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2cf1b26b-199d-4c7f-ab64-4805a9def2cc
> .
sub:targetpop
schema:healthCondition
<
http://purl.obolibrary.org/obo/DOID_1094
> .
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-1468-3557
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB" ;
npx:hasSignature
"DkAjfxxTQhAt2y8Mdxxmnbux6zOVZEp9/vDg9dsDFGpin+dmSwkUJhCLI3M9bOMk58crAs8rYIXu2fv2OCK3/zAJz9gVeu4Ieo5FLbGfxRABlpVabs9IX005HXwU5pEajt/r0Hf8WDjdXS/rKahyXn5Iz+WIp0piRkKq6SLpJiw=" ;
npx:hasSignatureTarget
this:
.
this:
dcterms:created
"2021-04-18T11:43:31.381+02:00"^^
xsd:dateTime
;
dcterms:creator
orcid:0000-0002-1468-3557
;
nt:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
nt:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
nt:wasCreatedFromTemplate
<
http://purl.org/np/RA56KBJXCfPObqVb3hNCSbbohzz02_VEW2PxnmyIQ0Hus
> .
}