@prefix nkg: <https://w3id.org/um/neurodkg/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix orcid: <https://orcid.org/> .
@prefix this: <http://purl.org/np/RAqSkTPJ9-z40DsO-RwUUlWlzbDfrbNIKAIxvdbHXI_RQ> .
@prefix sub: <http://purl.org/np/RAqSkTPJ9-z40DsO-RwUUlWlzbDfrbNIKAIxvdbHXI_RQ#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubInfo ;
    a np:Nanopublication .
}
sub:assertion {
  <http://purl.obolibrary.org/obo/HP_0000709> a bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/HP_0000709> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://identifiers.org/DRUGBANK:DB01224> ;
    a rdf:Statement ;
    rdfs:label "Psychosis is broadly defined as a disengagement from reality. It describes syndromes that impair both thought content and thought process. Psychosis negatively impacts an individual's quality of life, in addition to the families caring for them. Psychosis with different types of hallucinations and delusions occurs in the context of delirium. Neuropsychiatric symptoms (NPS) are almost universal in the course of common neurodegenerative disorders (NDD) like Alzheimer's disease (AD) or Parkinson's disease (PD). In this paper, the authors took an effort to characterize AD and PD psychosis with a special focus on the most diagnostically reliable features. Quetiapine (see supplement) is also commonly used in (off-label) for NPS in AD." ;
    bl:has_population_context sub:context ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:publications <https://pubmed.ncbi.nlm.nih.gov/30673880> ;
    bl:relation nkg:OffLabelIndication .
  sub:context a bl:Cohort ;
    rdfs:label "Adults" ;
    bl:has_phenotype <http://purl.obolibrary.org/obo/MONDO_0004975> .
  <https://identifiers.org/DRUGBANK:DB01224> a bl:Drug .
}
sub:provenance {
  sub:assertion prov:generatedAtTime "2021-08-24T19:42:40.705033"^^xsd:dateTime .
}
sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB" ;
    npx:hasSignature "HS9ZBtzgTOB/E8wSFwkSC6MZBLRC2I0NQe6qyFaov5LKLdX8EqYkeeltsFDiJsWf3rUTDH7ruOFiA6h0yqFzlj//25d620BaEk8EA155G2IaHnF8yfr4tiieq+Anoy5h9YV7rDdTiT3BIwd5LGUfW5Ct/x4B6V62Zz6vvMttQig=" ;
    npx:hasSignatureTarget this: .
  this: prov:generatedAtTime "2021-08-24T19:42:40.705033"^^xsd:dateTime ;
    prov:wasAttributedTo orcid:0000-0002-7641-6446 ;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
}