@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix this: <http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M> .
@prefix sub: <http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  biolink:FDA_adverse_event_level rdfs:label "FDA adverse event level - " .
  biolink:FDA_approval_status rdfs:label "FDA approval status - " .
  biolink:actively_involved_in rdfs:label "actively involved in - holds between a continuant and a process or function, where the continuant actively contributes to part or all of the process or function it realizes" .
  biolink:address rdfs:label "address - the particulars of the place where someone or an organization is situated. For now, this slot is a simple text \"blob\" containing all relevant details of the given location for fitness of purpose. For the moment, this \"address\" can include other contact details such as email and phone number(?)." .
  biolink:adjusted_p_value rdfs:label "adjusted p value - The adjusted p-value is the probability of obtaining test results at least as extreme as the results actually observed, under the assumption that the null hypothesis is correct, adjusted for multiple comparisons. P is always italicized and capitalized. The actual P value* should be expressed (P=. 04) rather than expressing a statement of inequality (P<. 05), unless P<." .
  biolink:affected_by rdfs:label "affected by - describes an entity of which the state or quality is affected by another existing entity." .
  biolink:affects rdfs:label "affects - describes an entity that has a direct affect on the state or quality of another existing entity. Use of the 'affects' predicate implies that the affected entity already exists, unlike predicates such as 'affects risk for' and 'prevents, where the outcome is something that may or may not come to be." .
  biolink:affects_risk_for rdfs:label "affects risk for - holds between two entities where exposure to one entity alters the chance of developing the other" .
  biolink:affiliation rdfs:label "affiliation - a professional relationship between one provider (often a person) within another provider (often an organization). Target provider identity should be specified by a CURIE. Providers may have multiple affiliations." .
  biolink:agent_id rdfs:label "agent id - Different classes of agents have distinct preferred identifiers. For publishers, use the ISBN publisher code. See https://grp.isbn-international.org/ for publisher code lookups. For editors, authors and individual providers, use the individual's ORCID if available; Otherwise, a ScopusID, ResearchID or Google Scholar ID ('GSID') may be used if the author ORCID is unknown. Institutional agents could be identified by an International Standard Name Identifier ('ISNI') code." .
  biolink:agent_name rdfs:label "agent name - it is recommended that an author's 'name' property be formatted as \"surname, firstname initial.\"" .
  biolink:aggregator_knowledge_source rdfs:label "aggregator knowledge source - An intermediate aggregator resource from which knowledge expressed in an Association was retrieved downstream of the original source, on its path to its current serialized form." .
  biolink:ameliorates rdfs:label "ameliorates - A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure, clinical intervention) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition." .
  biolink:anatomical_context_qualifier rdfs:label "anatomical context qualifier - A statement qualifier representing an anatomical location where an relationship expressed in an association took place (can be a tissue, cell type, or sub-cellular location)." .
  biolink:anatomical_entity_to_anatomical_entity_association_object rdfs:label "anatomical entity to anatomical entity association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:anatomical_entity_to_anatomical_entity_association_subject rdfs:label "anatomical entity to anatomical entity association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:anatomical_entity_to_anatomical_entity_ontogenic_association_object rdfs:label "anatomical entity to anatomical entity ontogenic association object - the structure at an earlier time" .
  biolink:anatomical_entity_to_anatomical_entity_ontogenic_association_predicate rdfs:label "anatomical entity to anatomical entity ontogenic association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:anatomical_entity_to_anatomical_entity_ontogenic_association_subject rdfs:label "anatomical entity to anatomical entity ontogenic association subject - the structure at a later time" .
  biolink:anatomical_entity_to_anatomical_entity_part_of_association_object rdfs:label "anatomical entity to anatomical entity part of association object - the whole" .
  biolink:anatomical_entity_to_anatomical_entity_part_of_association_predicate rdfs:label "anatomical entity to anatomical entity part of association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:anatomical_entity_to_anatomical_entity_part_of_association_subject rdfs:label "anatomical entity to anatomical entity part of association subject - the part" .
  biolink:animal_model_available_from rdfs:label "animal model available from - " .
  biolink:article_iso_abbreviation rdfs:label "article iso abbreviation - Optional value, if used locally as a convenience, is set to the iso abbreviation of the 'published in' parent." .
  biolink:article_published_in rdfs:label "article published in - The enclosing parent serial containing the article should have industry-standard identifier from ISSN." .
  biolink:aspect_qualifier rdfs:label "aspect qualifier - Composes with the core concept to describe new concepts of a different ontological type. e.g. a process in which the core concept participates, a function/activity/role held by the core concept, or a characteristic/quality that inheres in the core concept. The purpose of the aspect slot is to indicate what aspect is being affected in an 'affects' association." .
  biolink:assesses rdfs:label "assesses - The effect of a thing on a target was interrogated in some assay. A relationship between some perturbing agent (usually a chemical compound) and some target entity, where the affect of the perturbing agent on the target entity was interrogated in a particular assay. The target might be a particular protein, tissue, phenotype, whole organism, cell line, or other type of biological entity." .
  biolink:associated_environmental_context rdfs:label "associated environmental context - An attribute that can be applied to an association where the association holds between two entities located or occurring in a particular environment. For example, two microbial taxa may interact in the context of a human gut; a disease may give rise to a particular phenotype in a particular environmental exposure. # TODO: add examples of values for this property." .
  biolink:associated_with rdfs:label "associated with - Expresses a relationship between two named things where the relationship is typically generated statistically (though not in all cases), and is weaker than its child, 'correlated with', but stronger than its parent, 'related to'. This relationship holds between two concepts represented by variables for which a statistical dependence is demonstrated. E.g. the statement “Atrial Fibrillation (Afib) is associated with Myocardial Infarction (MI)” asserts that having Afib is not statistically independent from whether a patient will also have MI. Note that in Translator associations, the subject and object concepts may map exactly to the statistical variables, or represent related entities for which the variables serve as proxies in an Association (e.g. diseases, chemical entities or processes)." .
  biolink:associated_with_decreased_likelihood_of rdfs:label "associated with decreased likelihood of - Expresses a relationship between two named things where the relationship is typically generated statistically and the state or fact of something is less probable." .
  biolink:associated_with_increased_likelihood_of rdfs:label "associated with increased likelihood of - Expresses a relationship between two named things where the relationship is typically generated statistically and the state or fact of something is more probable." .
  biolink:associated_with_likelihood_of rdfs:label "associated with likelihood of - A a relationship that holds between two concepts represented by variables for which a statistical dependence is demonstrated, wherein the state or value of one variable predicts the future state or value of the other. E.g. the statement “An Atrial Fibrillation (Afib) diagnosis is associated with likelihood of a Myocardial Infarction (MI) diagnosis” asserts that the state of having Afib is associated with an increased or decreased likelihood that a patient will later exhibit MI." .
  biolink:associated_with_resistance_to rdfs:label "associated with resistance to - A relation that holds between a named thing and a chemical that specifies that the change in the named thing is found to be associated with the degree of resistance to treatment by the chemical." .
  biolink:associated_with_sensitivity_to rdfs:label "associated with sensitivity to - A relation that holds between a named thing and a chemical that specifies that the change in the named thing is found to be associated with the degree of sensitivity to treatment by the chemical." .
  biolink:association_category rdfs:label """association category - Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class.
* In a neo4j database this MAY correspond to the neo4j label tag.
* In an RDF database it should be a biolink model class URI.
This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`, ...
In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature `f` may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing}""" .
  biolink:association_slot rdfs:label "association slot - any slot that relates an association to another entity" .
  biolink:association_type rdfs:label "association type - rdf:type of biolink:Association should be fixed at rdf:Statement" .
  biolink:attribute_name rdfs:label "attribute name - The human-readable 'attribute name' can be set to a string which reflects its context of interpretation, e.g. SEPIO evidence/provenance/confidence annotation or it can default to the name associated with the 'has attribute type' slot ontology term." .
  biolink:author rdfs:label "author - an instance of one (co-)creator primarily responsible for a written work" .
  biolink:authors rdfs:label "authors - connects an publication to the list of authors who contributed to the publication. This property should be a comma-delimited list of author names. It is recommended that an author's name be formatted as \"surname, firstname initial.\". Note that this property is a node annotation expressing the citation list of authorship which might typically otherwise be more completely documented in biolink:PublicationToProviderAssociation defined edges which point to full details about an author and possibly, some qualifiers which clarify the specific status of a given author in the publication." .
  biolink:available_from rdfs:label "available from - " .
  biolink:base_coordinate rdfs:label "base coordinate - A position in the base coordinate system. Base coordinates start at position 1 instead of position 0." .
  biolink:behavior_to_behavioral_feature_association_object rdfs:label "behavior to behavioral feature association object - behavioral feature that is the object of the association" .
  biolink:behavior_to_behavioral_feature_association_subject rdfs:label "behavior to behavioral feature association subject - behavior that is the subject of the association" .
  biolink:binds rdfs:label "binds - A causal mechanism mediated by the direct contact between effector and target chemical or biomolecular entity, which form a stable physical interaction." .
  biolink:biological_role_mixin rdfs:label "biological role mixin - A role played by the chemical entity or part thereof within a biological context." .
  biolink:biomarker_for rdfs:label "biomarker for - holds between a measurable chemical entity and a disease or phenotypic feature, where the entity is used as an indicator of the presence or state of the disease or feature." .
  biolink:bonferonni_adjusted_p_value rdfs:label "bonferonni adjusted p value - The Bonferroni correction is an adjustment made to P values when several dependent or independent statistical tests are being performed simultaneously on a single data set. To perform a Bonferroni correction, divide the critical P value (α) by the number of comparisons being made. P is always italicized and capitalized. The actual P value* should be expressed (P=. 04) rather than expressing a statement of inequality (P<. 05), unless P<." .
  biolink:book_chapter_published_in rdfs:label "book chapter published in - The enclosing parent book containing the chapter should have industry-standard identifier from ISBN." .
  biolink:book_id rdfs:label "book id - Books should have industry-standard identifier such as from ISBN." .
  biolink:book_type rdfs:label "book type - Should generally be set to an ontology class defined term for 'book'." .
  biolink:broad_match rdfs:label "broad match - a list of terms from different schemas or terminology systems that have a broader, more general meaning. Broader terms are typically shown as parents in a hierarchy or tree." .
  biolink:broad_matches rdfs:label "broad matches - A list of terms from different schemas or terminology systems that have a broader meaning. Such terms often describe a more general concept from different ontological perspectives." .
  biolink:capable_of rdfs:label "capable of - holds between a physical entity and process or function, where the continuant alone has the ability to carry out the process or function." .
  biolink:case_to_entity_association_mixin_subject rdfs:label "case to entity association mixin subject - the case (e.g. patient) that has the property" .
  biolink:catalyst_qualifier rdfs:label "catalyst qualifier - a qualifier that connects an association between two causally connected entities (for example, two chemical entities, or a chemical entity in that changes location) and the gene product, gene, or complex that enables or catalyzes the change." .
  biolink:category rdfs:label """category - Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class.
* In a neo4j database this MAY correspond to the neo4j label tag.
* In an RDF database it should be a biolink model class URI.
This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`, ...
In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature `f` may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing}""" .
  biolink:causal_mechanism_qualifier rdfs:label "causal mechanism qualifier - A statement qualifier representing a type of molecular control mechanism through which an effect of a chemical on a gene or gene product is mediated (e.g. 'agonism', 'inhibition', 'allosteric modulation', 'channel blocker')" .
  biolink:caused_by rdfs:label "caused by - holds between two entities where the occurrence, existence, or activity of one is caused by the occurrence or generation of the other" .
  biolink:causes rdfs:label "causes - holds between two entities where the occurrence, existence, or activity of one causes the occurrence or generation of the other" .
  biolink:cell_line_as_a_model_of_disease_association_subject rdfs:label "cell line as a model of disease association subject - A cell line derived from an organismal entity with a disease state that is used as a model of that disease." .
  biolink:cell_line_to_disease_or_phenotypic_feature_association_subject rdfs:label "cell line to disease or phenotypic feature association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:cell_line_to_entity_association_mixin_subject rdfs:label "cell line to entity association mixin subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:chapter rdfs:label "chapter - chapter of a book" .
  biolink:chemical_affects_gene_association_anatomical_context_qualifier rdfs:label "chemical affects gene association anatomical context qualifier - A statement qualifier representing an anatomical location where an relationship expressed in an association took place (can be a tissue, cell type, or sub-cellular location)." .
  biolink:chemical_affects_gene_association_causal_mechanism_qualifier rdfs:label "chemical affects gene association causal mechanism qualifier - A statement qualifier representing a type of molecular control mechanism through which an effect of a chemical on a gene or gene product is mediated (e.g. 'agonism', 'inhibition', 'allosteric modulation', 'channel blocker')" .
  biolink:chemical_affects_gene_association_object rdfs:label "chemical affects gene association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:chemical_affects_gene_association_predicate rdfs:label "chemical affects gene association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:chemical_affects_gene_association_qualified_predicate rdfs:label "chemical affects gene association qualified predicate - Predicate to be used in an association when subject and object qualifiers are present and the full reading of the statement requires a qualification to the predicate in use in order to refine or increase the specificity of the full statement reading. This qualifier holds a relationship to be used instead of that expressed by the primary predicate, in a ‘full statement’ reading of the association, where qualifier-based semantics are included. This is necessary only in cases where the primary predicate does not work in a full statement reading." .
  biolink:chemical_affects_gene_association_species_context_qualifier rdfs:label "chemical affects gene association species context qualifier - A statement qualifier representing a taxonomic category of species in which a relationship expressed in an association took place." .
  biolink:chemical_affects_gene_association_subject rdfs:label "chemical affects gene association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:chemical_entity_assesses_named_thing_association_object rdfs:label "chemical entity assesses named thing association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:chemical_entity_assesses_named_thing_association_predicate rdfs:label "chemical entity assesses named thing association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:chemical_entity_assesses_named_thing_association_subject rdfs:label "chemical entity assesses named thing association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:chemical_entity_or_gene_or_gene_product_regulates_gene_association_object rdfs:label "chemical entity or gene or gene product regulates gene association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:chemical_entity_or_gene_or_gene_product_regulates_gene_association_predicate rdfs:label "chemical entity or gene or gene product regulates gene association predicate - the direction is always from regulator to regulated" .
  biolink:chemical_entity_or_gene_or_gene_product_regulates_gene_association_subject rdfs:label "chemical entity or gene or gene product regulates gene association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:chemical_entity_to_entity_association_mixin_subject rdfs:label "chemical entity to entity association mixin subject - the chemical entity that is an interactor" .
  biolink:chemical_gene_interaction_association_anatomical_context_qualifier rdfs:label "chemical gene interaction association anatomical context qualifier - A statement qualifier representing an anatomical location where an relationship expressed in an association took place (can be a tissue, cell type, or sub-cellular location)." .
  biolink:chemical_gene_interaction_association_object rdfs:label "chemical gene interaction association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:chemical_gene_interaction_association_predicate rdfs:label "chemical gene interaction association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:chemical_gene_interaction_association_subject rdfs:label "chemical gene interaction association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:chemical_or_drug_or_treatment_side_effect_disease_or_phenotypic_feature_association_predicate rdfs:label "chemical or drug or treatment side effect disease or phenotypic feature association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:chemical_or_drug_or_treatment_to_disease_or_phenotypic_feature_association_predicate rdfs:label "chemical or drug or treatment to disease or phenotypic feature association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:chemical_role_mixin rdfs:label "chemical role mixin - A role played by the chemical entity or part thereof within a chemical context." .
  biolink:chemical_to_chemical_association_object rdfs:label "chemical to chemical association object - the chemical element that is the target of the statement" .
  biolink:chemical_to_chemical_derivation_association_catalyst_qualifier rdfs:label "chemical to chemical derivation association catalyst qualifier - this connects the derivation edge to the chemical entity that catalyzes the reaction that causes the subject chemical to transform into the object chemical." .
  biolink:chemical_to_chemical_derivation_association_object rdfs:label "chemical to chemical derivation association object - the downstream chemical entity" .
  biolink:chemical_to_chemical_derivation_association_predicate rdfs:label "chemical to chemical derivation association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:chemical_to_chemical_derivation_association_subject rdfs:label "chemical to chemical derivation association subject - the upstream chemical entity" .
  biolink:chemical_to_disease_or_phenotypic_feature_association_object rdfs:label "chemical to disease or phenotypic feature association object - the disease or phenotype that is affected by the chemical" .
  biolink:chemical_to_entity_association_mixin_subject rdfs:label "chemical to entity association mixin subject - the chemical entity or entity that is an interactor" .
  biolink:chemical_to_pathway_association_object rdfs:label "chemical to pathway association object - the pathway that is affected by the chemical" .
  biolink:chemical_to_pathway_association_subject rdfs:label "chemical to pathway association subject - the chemical entity that is affecting the pathway" .
  biolink:chemically_similar_to rdfs:label "chemically similar to - holds between one small molecule entity and another that it approximates for purposes of scientific study, in virtue of its exhibiting similar features of the studied entity." .
  biolink:chi_squared_statistic rdfs:label "chi squared statistic - represents the chi-squared statistic computed from observations" .
  biolink:clinical_finding_has_attribute rdfs:label "clinical finding has attribute - connects any entity to an attribute" .
  biolink:clinical_measurement_has_attribute_type rdfs:label "clinical measurement has attribute type - connects an attribute to a class that describes it" .
  biolink:clinical_modifier_qualifier rdfs:label "clinical modifier qualifier - the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals." .
  biolink:close_match rdfs:label "close match - a list of terms from different schemas or terminology systems that have a semantically similar but not strictly equivalent, broader, or narrower meaning. Such terms often describe the same general concept from different ontological perspectives (e.g. drug as a type of chemical entity versus drug as a type of role borne by a chemical entity)." .
  biolink:coexists_with rdfs:label "coexists with - holds between two entities that are co-located in the same aggregate object, process, or spatio-temporal region" .
  biolink:coexpressed_with rdfs:label "coexpressed with - holds between any two genes or gene products, in which both are generally expressed within a single defined experimental context." .
  biolink:colocalizes_with rdfs:label "colocalizes with - holds between two entities that are observed to be located in the same place." .
  biolink:composed_primarily_of rdfs:label "composed primarily of - x composed_primarily_of_y if:more than half of the mass of x is made from parts of y." .
  biolink:concept_count_object rdfs:label "concept count object - The number of instances in a dataset/cohort whose records contain the concept in the object slot of an association." .
  biolink:concept_count_subject rdfs:label "concept count subject - The number of instances in a dataset/cohort whose records contain the concept in the subject slot of an association." .
  biolink:concept_pair_count rdfs:label "concept pair count - The number of instances in a dataset/cohort whose records contain both the subject and object concept of an association." .
  biolink:condition_associated_with_gene rdfs:label "condition associated with gene - holds between a gene and a disease or phenotypic feature that may be influenced, contribute to, or be correlated with the gene or its alleles/products" .
  biolink:context_qualifier rdfs:label "context qualifier - Restricts the setting/context/location where the core concept (or qualified core concept) resides or occurs." .
  biolink:contraindicated_for rdfs:label "contraindicated for - Holds between a drug and a disease or phenotype, such that a person with that disease should not be treated with the drug." .
  biolink:contributes_to rdfs:label "contributes to - holds between two entities where the occurrence, existence, or activity of one causes or contributes to the occurrence or generation of the other" .
  biolink:contributor_association_object rdfs:label "contributor association object - agent helping to realise the given entity (e.g. such as a publication)" .
  biolink:contributor_association_predicate rdfs:label "contributor association predicate - generally one of the predicate values 'provider', 'publisher', 'editor' or 'author'" .
  biolink:contributor_association_qualifiers rdfs:label "contributor association qualifiers - this field can be used to annotate special characteristics of an agent relationship, such as the fact that a given author agent of a publication is the 'corresponding author'" .
  biolink:contributor_association_subject rdfs:label "contributor association subject - information content entity which an agent has helped realise" .
  biolink:correlated_with rdfs:label "correlated with - A relationship that holds between two concepts represented by variables for which a statistical dependence is demonstrated using a correlation analysis method." .
  biolink:creation_date rdfs:label "creation date - date on which an entity was created. This can be applied to nodes or edges" .
  biolink:decreased_likelihood_associated_with rdfs:label "decreased likelihood associated with - " .
  biolink:decreases_amount_or_activity_of rdfs:label "decreases amount or activity of - A grouping mixin to help with searching for all the predicates that decrease the amount or activity of the object." .
  biolink:decreases_response_to rdfs:label "decreases response to - holds between two chemical entities where the action or effect of one decreases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other" .
  biolink:derivative_qualifier rdfs:label "derivative qualifier - A qualifier that composes with a core subject/object concept to describe something that is derived from the core concept. For example, the qualifier ‘metabolite’ combines with a ‘Chemical X’ core concept to express the composed concept ‘a metabolite of Chemical X’." .
  biolink:derives_from rdfs:label "derives from - holds between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity" .
  biolink:derives_into rdfs:label "derives into - holds between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity" .
  biolink:description rdfs:label "description - a human-readable description of an entity" .
  biolink:diagnoses rdfs:label "diagnoses - a relationship that identifies the nature of (an illness or other problem) by examination of the symptoms." .
  biolink:direction_qualifier rdfs:label "direction qualifier - Composes with the core concept (+ aspect if provided) to describe a change in its direction or degree." .
  biolink:directly_physically_interacts_with rdfs:label "directly physically interacts with - A causal mechanism mediated by a direct contact between the effector and target entities (this contact may be weak or strong, transient or stable)." .
  biolink:disease_has_basis_in rdfs:label "disease has basis in - A relation that holds between a disease and an entity where the state of the entity has contribution to the disease." .
  biolink:disease_has_location rdfs:label "disease has location - A relationship between a disease and an anatomical entity where the disease has one or more features that are located in that entity." .
  biolink:disease_or_phenotypic_feature_to_entity_association_mixin_subject rdfs:label "disease or phenotypic feature to entity association mixin subject - disease or phenotype" .
  biolink:disease_or_phenotypic_feature_to_genetic_inheritance_association_object rdfs:label "disease or phenotypic feature to genetic inheritance association object - genetic inheritance associated with the specified disease or phenotypic feature." .
  biolink:disease_or_phenotypic_feature_to_genetic_inheritance_association_predicate rdfs:label "disease or phenotypic feature to genetic inheritance association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:disease_or_phenotypic_feature_to_location_association_object rdfs:label "disease or phenotypic feature to location association object - anatomical entity in which the disease or feature is found." .
  biolink:disease_to_entity_association_mixin_subject rdfs:label "disease to entity association mixin subject - disease class" .
  biolink:disease_to_phenotypic_feature_association_object rdfs:label "disease to phenotypic feature association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:disease_to_phenotypic_feature_association_subject rdfs:label "disease to phenotypic feature association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:disrupted_by rdfs:label "disrupted by - describes a relationship where the structure, function, or occurrence of one entity is degraded or interfered with by another." .
  biolink:disrupts rdfs:label "disrupts - describes a relationship where one entity degrades or interferes with the structure, function, or occurrence of another." .
  biolink:drug_regulatory_status_world_wide rdfs:label "drug regulatory status world wide - An agglomeration of drug regulatory status worldwide. Not specific to FDA." .
  biolink:drug_to_entity_association_mixin_subject rdfs:label "drug to entity association mixin subject - the drug that is an interactor" .
  biolink:drug_to_gene_association_object rdfs:label "drug to gene association object - the gene or gene product that is affected by the drug" .
  biolink:druggable_gene_to_disease_association_has_evidence rdfs:label "druggable gene to disease association has evidence - connects an association to an instance of supporting evidence" .
  biolink:druggable_gene_to_disease_association_predicate rdfs:label "druggable gene to disease association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:druggable_gene_to_disease_association_subject rdfs:label "druggable gene to disease association subject - gene in which variation is correlated with the disease in a protective manner, or if the product produced by the gene can be targeted by a small molecule and this leads to a protective or improving disease state." .
  biolink:editor rdfs:label "editor - editor of a compiled work such as a book or a periodical (newspaper or an academic journal). Note that in the case of publications which have a containing \"published in\" node property, the editor association may not be attached directly to the embedded child publication, but only made in between the parent's publication node and the editorial agent of the encompassing publication (e.g. only from the Book referenced by the 'published_in' property of a book chapter Publication node)." .
  biolink:enabled_by rdfs:label "enabled by - holds between a process and a physical entity, where the physical entity executes the process" .
  biolink:enables rdfs:label "enables - holds between a physical entity and a process, where the physical entity executes the process" .
  biolink:end_coordinate rdfs:label "end coordinate - The position at which the subject genomic entity ends on the chromosome or other entity to which it is located on." .
  biolink:end_interbase_coordinate rdfs:label "end interbase coordinate - The position at which the subject nucleic acid entity ends on the chromosome or other entity to which it is located on." .
  biolink:entity_to_disease_association_mixin_object rdfs:label "entity to disease association mixin object - disease" .
  biolink:entity_to_disease_or_phenotypic_feature_association_mixin_object rdfs:label "entity to disease or phenotypic feature association mixin object - disease or phenotype" .
  biolink:entity_to_exposure_event_association_mixin_object rdfs:label "entity to exposure event association mixin object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:entity_to_outcome_association_mixin_object rdfs:label "entity to outcome association mixin object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:entity_to_phenotypic_feature_association_mixin_object rdfs:label "entity to phenotypic feature association mixin object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:evidence_count rdfs:label "evidence count - The number of evidence instances that are connected to an association." .
  biolink:exacerbates rdfs:label "exacerbates - A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition." .
  biolink:exact_match rdfs:label "exact match - holds between two entities that have strictly equivalent meanings, with a high degree of confidence" .
  biolink:exact_matches rdfs:label "exact matches - A list of terms from different schemas or terminology systems that have an identical meaning. Such terms often describe the same concept from different ontological perspectives." .
  biolink:exon_to_transcript_relationship_object rdfs:label "exon to transcript relationship object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:exon_to_transcript_relationship_subject rdfs:label "exon to transcript relationship subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:expected_count rdfs:label "expected count - The expected (calculated) number of instances in a dataset/cohort whose records contain both the subject and object concept of an association if the subject and object concepts are independent." .
  biolink:exposure_event_to_phenotypic_feature_association_subject rdfs:label "exposure event to phenotypic feature association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:expressed_in rdfs:label "expressed in - holds between a gene or gene product and an anatomical entity in which it is expressed" .
  biolink:expresses rdfs:label "expresses - holds between an anatomical entity and gene or gene product that is expressed there" .
  biolink:expression_site rdfs:label "expression site - location in which gene or protein expression takes place. May be cell, tissue, or organ." .
  biolink:extraction_confidence_score rdfs:label "extraction confidence score - A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone." .
  biolink:food_component_of rdfs:label "food component of - holds between a one or more chemical entities present in food, irrespective of nutritional value (i.e. could also be a contaminant or additive)" .
  biolink:form_or_variant_qualifier rdfs:label "form or variant qualifier - A qualifier that composes with a core subject/object concept to define a specific type, variant, alternative version of this concept. The composed concept remains a subtype or instance of the core concept. For example, the qualifier ‘mutation’ combines with the core concept ‘Gene X’ to express the compose concept ‘a mutation of Gene X’." .
  biolink:frequency_qualifier rdfs:label "frequency qualifier - a qualifier used in a phenotypic association to state how frequent the phenotype is observed in the subject" .
  biolink:full_name rdfs:label "full name - a long-form human readable name for a thing" .
  biolink:functional_association_object rdfs:label "functional association object - class describing the activity, process or localization of the gene product" .
  biolink:functional_association_subject rdfs:label "functional association subject - gene, product or macromolecular complex that has the function associated with the GO term" .
  biolink:gene_as_a_model_of_disease_association_subject rdfs:label "gene as a model of disease association subject - A gene that has a role in modeling the disease. This may be a model organism ortholog of a known disease gene, or it may be a gene whose mutants recapitulate core features of the disease." .
  biolink:gene_associated_with_condition rdfs:label "gene associated with condition - holds between a gene and a disease or phenotypic feature that the gene or its alleles/products may influence, contribute to, or correlate with" .
  biolink:gene_expression_mixin_quantifier_qualifier rdfs:label "gene expression mixin quantifier qualifier - Optional quantitative value indicating degree of expression." .
  biolink:gene_fusion_with rdfs:label "gene fusion with - holds between two independent genes that have fused through translocation, interstitial deletion, or chromosomal inversion to form a new, hybrid gene. Fusion genes are often implicated in various neoplasms and cancers." .
  biolink:gene_has_variant_that_contributes_to_disease_association_object rdfs:label "gene has variant that contributes to disease association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:gene_has_variant_that_contributes_to_disease_association_predicate rdfs:label "gene has variant that contributes to disease association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:gene_has_variant_that_contributes_to_disease_association_subject rdfs:label "gene has variant that contributes to disease association subject - A gene that has a role in modeling the disease. This may be a model organism ortholog of a known disease gene, or it may be a gene whose mutants recapitulate core features of the disease." .
  biolink:gene_product_of rdfs:label "gene product of - definition x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of thatf process is either y or something that is ribosomally translated from x" .
  biolink:gene_to_disease_association_object rdfs:label "gene to disease association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:gene_to_disease_association_subject rdfs:label "gene to disease association subject - gene in which variation is correlated with the disease, may be protective or causative or associative, or as a model" .
  biolink:gene_to_entity_association_mixin_subject rdfs:label "gene to entity association mixin subject - gene that is the subject of the association" .
  biolink:gene_to_expression_site_association_object rdfs:label "gene to expression site association object - location in which the gene is expressed" .
  biolink:gene_to_expression_site_association_predicate rdfs:label "gene to expression site association predicate - expression relationship" .
  biolink:gene_to_expression_site_association_quantifier_qualifier rdfs:label "gene to expression site association quantifier qualifier - can be used to indicate magnitude, or also ranking" .
  biolink:gene_to_expression_site_association_stage_qualifier rdfs:label "gene to expression site association stage qualifier - stage at which the gene is expressed in the site" .
  biolink:gene_to_expression_site_association_subject rdfs:label "gene to expression site association subject - Gene or gene product positively within the specified anatomical entity (or subclass, i.e. cellular component) location." .
  biolink:gene_to_gene_association_object rdfs:label "gene to gene association object - the object gene in the association. If the relation is symmetric, subject vs object is arbitrary. We allow a gene product to stand as a proxy for the gene or vice versa." .
  biolink:gene_to_gene_association_subject rdfs:label "gene to gene association subject - the subject gene in the association. If the relation is symmetric, subject vs object is arbitrary. We allow a gene product to stand as a proxy for the gene or vice versa." .
  biolink:gene_to_gene_coexpression_association_predicate rdfs:label "gene to gene coexpression association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:gene_to_gene_family_association_object rdfs:label "gene to gene family association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:gene_to_gene_family_association_predicate rdfs:label "gene to gene family association predicate - membership of the gene in the given gene family." .
  biolink:gene_to_gene_family_association_subject rdfs:label "gene to gene family association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:gene_to_gene_homology_association_object rdfs:label "gene to gene homology association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:gene_to_gene_homology_association_predicate rdfs:label "gene to gene homology association predicate - homology relationship type" .
  biolink:gene_to_gene_homology_association_subject rdfs:label "gene to gene homology association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:gene_to_gene_product_relationship_object rdfs:label "gene to gene product relationship object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:gene_to_gene_product_relationship_predicate rdfs:label "gene to gene product relationship predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:gene_to_gene_product_relationship_subject rdfs:label "gene to gene product relationship subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:gene_to_go_term_association_object rdfs:label "gene to go term association object - class describing the activity, process or localization of the gene product" .
  biolink:gene_to_go_term_association_subject rdfs:label "gene to go term association subject - gene, product or macromolecular complex that has the function associated with the GO term" .
  biolink:gene_to_pathway_association_object rdfs:label "gene to pathway association object - the pathway that includes or is affected by the gene or gene product" .
  biolink:gene_to_pathway_association_subject rdfs:label "gene to pathway association subject - the gene or gene product entity that participates or influences the pathway" .
  biolink:gene_to_phenotypic_feature_association_object rdfs:label "gene to phenotypic feature association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:gene_to_phenotypic_feature_association_subject rdfs:label "gene to phenotypic feature association subject - gene in which variation is correlated with the phenotypic feature" .
  biolink:genetic_association rdfs:label "genetic association - Co-occurrence of a certain allele of a genetic marker and the phenotype of interest in the same individuals at above-chance level" .
  biolink:genetic_neighborhood_of rdfs:label "genetic neighborhood of - holds between two genes located nearby one another on a chromosome. " .
  biolink:genetically_interacts_with rdfs:label "genetically interacts with - holds between two genes whose phenotypic effects are dependent on each other in some way - such that their combined phenotypic effects are the result of some interaction between the activity of their gene products. Examples include epistasis and synthetic lethality." .
  biolink:genome_build rdfs:label "genome build - The version of the genome on which a feature is located. For example, GRCh38 for Homo sapiens." .
  biolink:genomic_sequence_localization_object rdfs:label "genomic sequence localization object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:genomic_sequence_localization_predicate rdfs:label "genomic sequence localization predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:genomic_sequence_localization_subject rdfs:label "genomic sequence localization subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:genotype_as_a_model_of_disease_association_subject rdfs:label "genotype as a model of disease association subject - A genotype that has a role in modeling the disease." .
  biolink:genotype_to_disease_association_object rdfs:label "genotype to disease association object - a disease that is associated with that genotype" .
  biolink:genotype_to_disease_association_predicate rdfs:label "genotype to disease association predicate - E.g. is pathogenic for" .
  biolink:genotype_to_disease_association_subject rdfs:label "genotype to disease association subject - a genotype that is associated in some way with a disease state" .
  biolink:genotype_to_entity_association_mixin_subject rdfs:label "genotype to entity association mixin subject - genotype that is the subject of the association" .
  biolink:genotype_to_gene_association_object rdfs:label "genotype to gene association object - gene implicated in genotype" .
  biolink:genotype_to_gene_association_predicate rdfs:label "genotype to gene association predicate - the relationship type used to connect genotype to gene" .
  biolink:genotype_to_gene_association_subject rdfs:label "genotype to gene association subject - parent genotype" .
  biolink:genotype_to_genotype_part_association_object rdfs:label "genotype to genotype part association object - child genotype" .
  biolink:genotype_to_genotype_part_association_predicate rdfs:label "genotype to genotype part association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:genotype_to_genotype_part_association_subject rdfs:label "genotype to genotype part association subject - parent genotype" .
  biolink:genotype_to_phenotypic_feature_association_predicate rdfs:label "genotype to phenotypic feature association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:genotype_to_phenotypic_feature_association_subject rdfs:label "genotype to phenotypic feature association subject - genotype that is associated with the phenotypic feature" .
  biolink:genotype_to_variant_association_object rdfs:label "genotype to variant association object - gene implicated in genotype" .
  biolink:genotype_to_variant_association_predicate rdfs:label "genotype to variant association predicate - the relationship type used to connect genotype to gene" .
  biolink:genotype_to_variant_association_subject rdfs:label "genotype to variant association subject - parent genotype" .
  biolink:has_active_ingredient rdfs:label "has active ingredient - holds between a drug and a molecular entity in which the latter is a part of the former, and is a biologically active component" .
  biolink:has_adverse_event rdfs:label "has adverse event - An untoward medical occurrence in a patient or clinical investigation subject that happens during treatment with a therapeutic agent. Adverse events may be caused by something other than the drug or therapy being given and may include abnormal laboratory finding, symptoms, or diseases temporally associated with the treatment, whether or not considered related to the treatment. Adverse events are unintended effects that occur when a medication is administered correctly." .
  biolink:has_attribute rdfs:label "has attribute - connects any entity to an attribute" .
  biolink:has_attribute_type rdfs:label "has attribute type - connects an attribute to a class that describes it" .
  biolink:has_biological_sequence rdfs:label "has biological sequence - connects a genomic feature to its sequence" .
  biolink:has_biomarker rdfs:label "has biomarker - holds between a disease or phenotypic feature and a measurable chemical entity that is used as an indicator of the presence or state of the disease or feature. # metabolite" .
  biolink:has_chemical_formula rdfs:label "has chemical formula - description of chemical compound based on element symbols" .
  biolink:has_chemical_role rdfs:label "has chemical role - A role is particular behaviour which a chemical entity may exhibit." .
  biolink:has_completed rdfs:label "has completed - holds between an entity and a process that the entity is capable of and has completed" .
  biolink:has_confidence_level rdfs:label "has confidence level - connects an association to a qualitative term denoting the level of confidence" .
  biolink:has_constituent rdfs:label "has constituent - one or more molecular entities within a chemical mixture" .
  biolink:has_count rdfs:label "has count - number of things with a particular property" .
  biolink:has_device rdfs:label "has device - connects an entity to one or more (medical) devices" .
  biolink:has_drug rdfs:label "has drug - connects an entity to one or more drugs" .
  biolink:has_evidence rdfs:label "has evidence - connects an association to an instance of supporting evidence" .
  biolink:has_excipient rdfs:label "has excipient - holds between a drug and a molecular entities in which the latter is a part of the former, and is a biologically inactive component" .
  biolink:has_food_component rdfs:label "has food component - holds between food and one or more chemical entities composing it, irrespective of nutritional value (i.e. could also be a contaminant or additive)" .
  biolink:has_gene rdfs:label "has gene - connects an entity associated with one or more genes" .
  biolink:has_gene_or_gene_product rdfs:label "has gene or gene product - connects an entity with one or more gene or gene products" .
  biolink:has_gene_product rdfs:label "has gene product - holds between a gene and a transcribed and/or translated product generated from it" .
  biolink:has_input rdfs:label "has input - holds between a process and a continuant, where the continuant is an input into the process" .
  biolink:has_member rdfs:label "has member - Defines a mereological relation between a collection and an item." .
  biolink:has_metabolite rdfs:label "has metabolite - holds between two molecular entities in which the second one is derived from the first one as a product of metabolism" .
  biolink:has_mode_of_inheritance rdfs:label "has mode of inheritance - Relates a disease or phenotypic feature to its observed genetic segregation and assumed associated underlying DNA manifestation (i.e. autosomal, sex or mitochondrial chromosome)." .
  biolink:has_molecular_consequence rdfs:label "has molecular consequence - connects a sequence variant to a class describing the molecular consequence. E.g. SO:0001583" .
  biolink:has_not_completed rdfs:label "has not completed - holds between an entity and a process that the entity is capable of, but has not completed" .
  biolink:has_numeric_value rdfs:label "has numeric value - connects a quantity value to a number" .
  biolink:has_nutrient rdfs:label "has nutrient - one or more nutrients which are growth factors for a living organism" .
  biolink:has_output rdfs:label "has output - holds between a process and a continuant, where the continuant is an output of the process" .
  biolink:has_part rdfs:label "has part - holds between wholes and their parts (material entities or processes)" .
  biolink:has_participant rdfs:label "has participant - holds between a process and a continuant, where the continuant is somehow involved in the process" .
  biolink:has_percentage rdfs:label "has percentage - equivalent to has quotient multiplied by 100" .
  biolink:has_phenotype rdfs:label "has phenotype - holds between a biological entity and a phenotype, where a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). In SNOMEDCT, disorders with keyword 'characterized by' should translate into this predicate." .
  biolink:has_plasma_membrane_part rdfs:label "has plasma membrane part - Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part." .
  biolink:has_procedure rdfs:label "has procedure - connects an entity to one or more (medical) procedures" .
  biolink:has_qualitative_value rdfs:label "has qualitative value - connects an attribute to a value" .
  biolink:has_quantitative_value rdfs:label "has quantitative value - connects an attribute to a value" .
  biolink:has_receptor rdfs:label "has receptor - the organism or organism part being exposed" .
  biolink:has_route rdfs:label "has route - the process that results in the stressor coming into direct contact with the receptor" .
  biolink:has_sequence_location rdfs:label "has sequence location - holds between two nucleic acid entities when the subject can be localized in sequence coordinates on the object. For example, between an exon and a chromosome/contig." .
  biolink:has_side_effect rdfs:label "has side effect - An unintended, but predictable, secondary effect shown to be correlated with a therapeutic agent, drug or treatment. Side effects happen at normal, recommended doses or treatments, and are unrelated to the intended purpose of the medication." .
  biolink:has_stressor rdfs:label "has stressor - the process or entity that the receptor is being exposed to" .
  biolink:has_supporting_study_result rdfs:label "has supporting study result - connects an association to an instance of supporting study result" .
  biolink:has_topic rdfs:label "has topic - Connects a node to a vocabulary term or ontology class that describes some aspect of the entity. In general specific characterization is preferred. See https://github.com/biolink/biolink-model/issues/238" .
  biolink:has_total rdfs:label "has total - total number of things in a particular reference set" .
  biolink:has_unit rdfs:label "has unit - connects a quantity value to a unit" .
  biolink:has_variant_part rdfs:label "has variant part - holds between a nucleic acid entity and a nucleic acid entity that is a sub-component of it" .
  biolink:highest_FDA_approval_status rdfs:label "highest FDA approval status - Should be the highest level of FDA approval this chemical entity or device has, regardless of which disease, condition or phenotype it is currently being reviewed to treat. For specific levels of FDA approval for a specific condition, disease, phenotype, etc., see the association slot, 'FDA approval status.'" .
  biolink:homologous_to rdfs:label "homologous to - holds between two biological entities that have common evolutionary origin" .
  biolink:id rdfs:label "id - A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI" .
  biolink:in_cell_population_with rdfs:label "in cell population with - holds between two genes or gene products that are expressed in the same cell type or population" .
  biolink:in_complex_with rdfs:label "in complex with - holds between two genes or gene products that are part of (or code for products that are part of) in the same macromolecular complex" .
  biolink:in_linkage_disequilibrium_with rdfs:label "in linkage disequilibrium with - holds between two sequence variants, the presence of which are correlated in a population" .
  biolink:in_pathway_with rdfs:label "in pathway with - holds between two genes or gene products that are part of in the same biological pathway" .
  biolink:in_taxon rdfs:label "in taxon - connects an entity to its taxonomic classification. Only certain kinds of entities can be taxonomically classified; see 'thing with taxon'" .
  biolink:increased_likelihood_associated_with rdfs:label "increased likelihood associated with - " .
  biolink:increases_amount_or_activity_of rdfs:label "increases amount or activity of - A grouping mixin to help with searching for all the predicates that increase the amount or activity of the object." .
  biolink:increases_response_to rdfs:label "increases response to - holds between two chemical entities where the action or effect of one increases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other" .
  biolink:information_content_entity_to_named_thing_association_object rdfs:label "information content entity to named thing association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:information_content_entity_to_named_thing_association_predicate rdfs:label "information content entity to named thing association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:information_content_entity_to_named_thing_association_subject rdfs:label "information content entity to named thing association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:interacts_with rdfs:label "interacts with - holds between any two entities that directly or indirectly interact with each other" .
  biolink:interbase_coordinate rdfs:label "interbase coordinate - A position in interbase coordinates. Interbase coordinates start at position 0 instead of position 1. This is applied to a sequence localization edge." .
  biolink:iri rdfs:label "iri - An IRI for an entity. This is determined by the id using expansion rules." .
  biolink:is_active_ingredient_of rdfs:label "is active ingredient of - holds between a molecular entity and a drug, in which the former is a part of the latter, and is a biologically active component" .
  biolink:is_excipient_of rdfs:label "is excipient of - holds between a molecular entity and a drug in which the former is a part of the latter, and is a biologically inactive component" .
  biolink:is_frameshift_variant_of rdfs:label "is frameshift variant of - holds between a sequence variant and a gene, such the sequence variant causes a disruption of the translational reading frame, because the number of nucleotides inserted or deleted is not a multiple of three." .
  biolink:is_metabolite rdfs:label "is metabolite - indicates whether a molecular entity is a metabolite" .
  biolink:is_metabolite_of rdfs:label "is metabolite of - holds between two molecular entities in which the first one is derived from the second one as a product of metabolism" .
  biolink:is_missense_variant_of rdfs:label "is missense variant of - holds between a gene and a sequence variant, such the sequence variant results in a different amino acid sequence but where the length is preserved." .
  biolink:is_nearby_variant_of rdfs:label "is nearby variant of - holds between a sequence variant and a gene sequence that the variant is genomically close to." .
  biolink:is_non_coding_variant_of rdfs:label "is non coding variant of - holds between a sequence variant and a gene, where the variant does not affect the coding sequence" .
  biolink:is_nonsense_variant_of rdfs:label "is nonsense variant of - holds between a sequence variant and a gene, such the sequence variant results in a premature stop codon" .
  biolink:is_sequence_variant_of rdfs:label "is sequence variant of - holds between a sequence variant and a nucleic acid entity" .
  biolink:is_splice_site_variant_of rdfs:label "is splice site variant of - holds between a sequence variant and a gene, such the sequence variant is in the canonical splice site of one of the gene's exons." .
  biolink:is_supplement rdfs:label "is supplement - " .
  biolink:is_synonymous_variant_of rdfs:label "is synonymous variant of - holds between a sequence variant and a gene, such the sequence variant is in the coding sequence of the gene, but results in the same amino acid sequence" .
  biolink:is_toxic rdfs:label "is toxic - " .
  biolink:iso_abbreviation rdfs:label "iso abbreviation - Standard abbreviation for periodicals in the International Organization for Standardization (ISO) 4 system See https://www.issn.org/services/online-services/access-to-the-ltwa/. If the 'published in' property is set, then the iso abbreviation pertains to the broader publication context (the journal) within which the given publication node is embedded, not the publication itself." .
  biolink:issue rdfs:label "issue - issue of a newspaper, a scientific journal or magazine for reference purpose" .
  biolink:keywords rdfs:label "keywords - keywords tagging a publication" .
  biolink:knowledge_source rdfs:label "knowledge source - An Information Resource from which the knowledge expressed in an Association was retrieved, directly or indirectly. This can be any resource through which the knowledge passed on its way to its currently serialized form. In practice, implementers should use one of the more specific subtypes of this generic property." .
  biolink:latitude rdfs:label "latitude - latitude" .
  biolink:likelihood_associated_with rdfs:label "likelihood associated with - " .
  biolink:ln_ratio rdfs:label "ln ratio - the natural log of the ratio of co-occurrence to expected" .
  biolink:ln_ratio_confidence_interval rdfs:label "ln ratio confidence interval - The 99% confidence interval for the ln_ratio calculation (i.e. the range of values within which the true value has a 99% chance of falling)" .
  biolink:located_in rdfs:label "located in - holds between a material entity and a material entity or site within which it is located (but of which it is not considered a part)" .
  biolink:location_of rdfs:label "location of - holds between material entity or site and a material entity that is located within it (but not considered a part of it)" .
  biolink:longitude rdfs:label "longitude - longitude" .
  biolink:macromolecular_machine_mixin_name rdfs:label "macromolecular machine mixin name - genes are typically designated by a short symbol and a full name. We map the symbol to the default display name and use an additional slot for full name" .
  biolink:macromolecular_machine_to_biological_process_association_object rdfs:label "macromolecular machine to biological process association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:macromolecular_machine_to_cellular_component_association_object rdfs:label "macromolecular machine to cellular component association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:macromolecular_machine_to_entity_association_mixin_subject rdfs:label "macromolecular machine to entity association mixin subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:macromolecular_machine_to_molecular_activity_association_object rdfs:label "macromolecular machine to molecular activity association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:manifestation_of rdfs:label "manifestation of - that part of a phenomenon which is directly observable or visibly expressed, or which gives evidence to the underlying process; used in SemMedDB for linking things like dysfunctions and processes to some disease or syndrome" .
  biolink:mapped_predicate rdfs:label "mapped predicate - The predicate that is being replaced by the fully qualified representation of predicate + subject and object qualifiers. Only to be used in test data and mapping data to help with the transition to the fully qualified predicate model. Not to be used in knowledge graphs." .
  biolink:material_sample_derivation_association_object rdfs:label "material sample derivation association object - the material entity the sample was derived from. This may be another material sample, or any other material entity, including for example an organism, a geographic feature, or some environmental material." .
  biolink:material_sample_derivation_association_predicate rdfs:label "material sample derivation association predicate - derivation relationship" .
  biolink:material_sample_derivation_association_subject rdfs:label "material sample derivation association subject - the material sample being described" .
  biolink:material_sample_to_entity_association_mixin_subject rdfs:label "material sample to entity association mixin subject - the material sample being described" .
  biolink:max_tolerated_dose rdfs:label "max tolerated dose - The highest dose of a drug or treatment that does not cause unacceptable side effects. The maximum tolerated dose is determined in clinical trials by testing increasing doses on different groups of people until the highest dose with acceptable side effects is found. Also called MTD." .
  biolink:mechanism_of_action rdfs:label "mechanism of action - a boolean flag to indicate if the edge is part of a path or subgraph of a knowledge graph that constitutes the mechanism of action for a result." .
  biolink:member_of rdfs:label "member of - Defines a mereological relation between a item and a collection." .
  biolink:mentioned_by rdfs:label "mentioned by - refers to is a relation between one named thing and the information content entity that it makes reference to." .
  biolink:mentions rdfs:label "mentions - refers to is a relation between one information content entity and the named thing that it makes reference to." .
  biolink:mesh_terms rdfs:label "mesh terms - mesh terms tagging a publication" .
  biolink:model_of rdfs:label "model of - holds between a thing and some other thing it approximates for purposes of scientific study, in virtue of its exhibiting similar features of the studied entity." .
  biolink:model_to_disease_association_mixin_predicate rdfs:label "model to disease association mixin predicate - The relationship to the disease" .
  biolink:model_to_disease_association_mixin_subject rdfs:label "model to disease association mixin subject - The entity that serves as the model of the disease. This may be an organism, a strain of organism, a genotype or variant that exhibits similar features, or a gene that when mutated exhibits features of the disease" .
  biolink:molecular_activity_enabled_by rdfs:label "molecular activity enabled by - The gene product, gene, or complex that catalyzes the reaction" .
  biolink:molecular_activity_has_input rdfs:label "molecular activity has input - A chemical entity that is the input for the reaction" .
  biolink:molecular_activity_has_output rdfs:label "molecular activity has output - A chemical entity that is the output for the reaction" .
  biolink:molecular_activity_to_chemical_entity_association_object rdfs:label "molecular activity to chemical entity association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:molecular_activity_to_chemical_entity_association_subject rdfs:label "molecular activity to chemical entity association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:molecular_activity_to_molecular_activity_association_object rdfs:label "molecular activity to molecular activity association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:molecular_activity_to_molecular_activity_association_subject rdfs:label "molecular activity to molecular activity association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:molecular_activity_to_pathway_association_object rdfs:label "molecular activity to pathway association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:molecular_activity_to_pathway_association_predicate rdfs:label "molecular activity to pathway association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:molecular_activity_to_pathway_association_subject rdfs:label "molecular activity to pathway association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:name rdfs:label "name - A human-readable name for an attribute or entity." .
  biolink:named_thing_associated_with_likelihood_of_named_thing_association_predicate rdfs:label "named thing associated with likelihood of named thing association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:named_thing_category rdfs:label """named thing category - Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class.
* In a neo4j database this MAY correspond to the neo4j label tag.
* In an RDF database it should be a biolink model class URI.
This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`, ...
In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature `f` may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing}""" .
  biolink:narrow_match rdfs:label "narrow match - a list of terms from different schemas or terminology systems that have a narrower, more specific meaning. Narrower terms are typically shown as children in a hierarchy or tree." .
  biolink:narrow_matches rdfs:label "narrow matches - A list of terms from different schemas or terminology systems that have a narrower meaning. Such terms often describe a more specific concept from different ontological perspectives." .
  biolink:negated rdfs:label "negated - if set to true, then the association is negated i.e. is not true" .
  biolink:negatively_correlated_with rdfs:label "negatively correlated with - A relationship that holds between two concepts represented by variables for which a statistical correlation is demonstrated, wherein variable values move in opposite directions (i.e. increased in one or presence of one correlates with a decrease or absence of the other)." .
  biolink:node_property rdfs:label "node property - A grouping for any property that holds between a node and a value" .
  biolink:nutrient_of rdfs:label "nutrient of - holds between a one or more chemical entities present in food, irrespective of nutritional value (i.e. could also be a contaminant or additive)" .
  biolink:object rdfs:label "object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:object_location_in_text rdfs:label "object location in text - Character offsets for the text span(s) in the supporting text corresponding to the object concept of the extracted assertion" .
  biolink:occurs_in rdfs:label "occurs in - holds between a process and a material entity or site within which the process occurs" .
  biolink:occurs_together_in_literature_with rdfs:label "occurs together in literature with - holds between two entities where their co-occurrence is correlated by counts of publications in which both occur, using some threshold of occurrence as defined by the edge provider." .
  biolink:onset_qualifier rdfs:label "onset qualifier - a qualifier used in a phenotypic association to state when the phenotype appears is in the subject" .
  biolink:opposite_of rdfs:label "opposite of - x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x). (This description is from RO. Needs to be rephrased)." .
  biolink:organism_taxon_to_entity_association_subject rdfs:label "organism taxon to entity association subject - organism taxon that is the subject of the association" .
  biolink:organism_taxon_to_environment_association_object rdfs:label "organism taxon to environment association object - the environment in which the organism occurs" .
  biolink:organism_taxon_to_environment_association_predicate rdfs:label "organism taxon to environment association predicate - predicate describing the relationship between the taxon and the environment" .
  biolink:organism_taxon_to_environment_association_subject rdfs:label "organism taxon to environment association subject - the taxon that is the subject of the association" .
  biolink:organism_taxon_to_organism_taxon_association_object rdfs:label "organism taxon to organism taxon association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:organism_taxon_to_organism_taxon_association_subject rdfs:label "organism taxon to organism taxon association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:organism_taxon_to_organism_taxon_interaction_associated_environmental_context rdfs:label "organism taxon to organism taxon interaction associated environmental context - the environment in which the two taxa interact" .
  biolink:organism_taxon_to_organism_taxon_interaction_object rdfs:label "organism taxon to organism taxon interaction object - the taxon that is the subject of the association" .
  biolink:organism_taxon_to_organism_taxon_interaction_predicate rdfs:label "organism taxon to organism taxon interaction predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:organism_taxon_to_organism_taxon_interaction_subject rdfs:label "organism taxon to organism taxon interaction subject - the taxon that is the subject of the association" .
  biolink:organism_taxon_to_organism_taxon_specialization_object rdfs:label "organism taxon to organism taxon specialization object - the more general taxon" .
  biolink:organism_taxon_to_organism_taxon_specialization_predicate rdfs:label "organism taxon to organism taxon specialization predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:organism_taxon_to_organism_taxon_specialization_subject rdfs:label "organism taxon to organism taxon specialization subject - the more specific taxon" .
  biolink:organism_to_organism_association_object rdfs:label "organism to organism association object - An association between two individual organisms." .
  biolink:organism_to_organism_association_subject rdfs:label "organism to organism association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:organismal_entity_as_a_model_of_disease_association_subject rdfs:label "organismal entity as a model of disease association subject - A organismal entity (strain, breed) with a predisposition to a disease, or bred/created specifically to model a disease." .
  biolink:organismal_entity_has_attribute rdfs:label "organismal entity has attribute - may often be an organism attribute" .
  biolink:original_object rdfs:label "original object - used to hold the original object of a relation (or predicate) that an external knowledge source uses before transformation to match the biolink-model specification." .
  biolink:original_predicate rdfs:label "original predicate - used to hold the original relation/predicate that an external knowledge source uses before transformation to match the biolink-model specification." .
  biolink:original_subject rdfs:label "original subject - used to hold the original subject of a relation (or predicate) that an external knowledge source uses before transformation to match the biolink-model specification." .
  biolink:orthologous_to rdfs:label "orthologous to - a homology relationship between entities (typically genes) that diverged after a speciation event." .
  biolink:overlaps rdfs:label "overlaps - holds between entities that overlap in their extents (materials or processes)" .
  biolink:p_value rdfs:label "p value - A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone." .
  biolink:pages rdfs:label "pages - page number of source referenced for statement or publication" .
  biolink:pairwise_gene_to_gene_interaction_predicate rdfs:label "pairwise gene to gene interaction predicate - interaction relationship type" .
  biolink:pairwise_molecular_interaction_id rdfs:label "pairwise molecular interaction id - identifier for the interaction. This may come from an interaction database such as IMEX." .
  biolink:pairwise_molecular_interaction_object rdfs:label "pairwise molecular interaction object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:pairwise_molecular_interaction_predicate rdfs:label "pairwise molecular interaction predicate - interaction relationship type" .
  biolink:pairwise_molecular_interaction_subject rdfs:label "pairwise molecular interaction subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:paralogous_to rdfs:label "paralogous to - a homology relationship that holds between entities (typically genes) that diverged after a duplication event." .
  biolink:part_of rdfs:label "part of - holds between parts and wholes (material entities or processes)" .
  biolink:part_qualifier rdfs:label "part qualifier - defines a specific part/component of the core concept (used in cases there this specific part has no IRI we can use to directly represent it, e.g. 'ESR1 transcript' q: polyA tail)." .
  biolink:participates_in rdfs:label "participates in - holds between a continuant and a process, where the continuant is somehow involved in the process" .
  biolink:phase rdfs:label "phase - The phase for a coding sequence entity. For example, phase of a CDS as represented in a GFF3 with a value of 0, 1 or 2." .
  biolink:phenotypic_state rdfs:label "phenotypic state - in experiments (e.g. gene expression) assaying diseased or unhealthy tissue, the phenotypic state can be put here, e.g. MONDO ID. For healthy tissues, use XXX." .
  biolink:physically_interacts_with rdfs:label "physically interacts with - holds between two entities that make physical contact as part of some interaction. does not imply a causal relationship." .
  biolink:population_context_qualifier rdfs:label "population context qualifier - a biological population (general, study, cohort, etc.) with a specific set of characteristics to constrain an association." .
  biolink:population_to_population_association_object rdfs:label "population to population association object - the population that form the object of the association" .
  biolink:population_to_population_association_predicate rdfs:label "population to population association predicate - A relationship type that holds between the subject and object populations. Standard mereological relations can be used. E.g. subject part-of object, subject overlaps object. Derivation relationships can also be used" .
  biolink:population_to_population_association_subject rdfs:label "population to population association subject - the population that form the subject of the association" .
  biolink:positively_correlated_with rdfs:label "positively correlated with - A relationship that holds between two concepts represented by variables for which a statistical correlation is demonstrated, wherein variable values move together in the same direction (i.e. increased in one or presence of one correlates with an increase or presence of the other)." .
  biolink:preceded_by rdfs:label "preceded by - holds between two processes, where the other is completed before the one begins" .
  biolink:precedes rdfs:label "precedes - holds between two processes, where one completes before the other begins" .
  biolink:predicate rdfs:label "predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:predicate_mappings rdfs:label "predicate mappings - A collection of relationships that are not used in biolink, but have biolink patterns that can be used to replace them. This is a temporary slot to help with the transition to the fully qualified predicate model in Biolink3." .
  biolink:predisposes rdfs:label "predisposes - holds between two entities where exposure to one entity increases the chance of developing the other" .
  biolink:prevented_by rdfs:label "prevented by - holds between a potential outcome of which the likelihood was reduced by the application or use of an entity." .
  biolink:prevents rdfs:label "prevents - holds between an entity whose application or use reduces the likelihood of a potential outcome. Typically used to associate a chemical entity, exposure, activity, or medical intervention that can prevent the onset a disease or phenotypic feature." .
  biolink:primary_knowledge_source rdfs:label "primary knowledge source - The most upstream source of the knowledge expressed in an Association that an implementer can identify. Performing a rigorous analysis of upstream data providers is expected; every effort is made to catalog the most upstream source of data in this property. Only one data source should be declared primary in any association. \"aggregator knowledge source\" can be used to caputre non-primary sources." .
  biolink:produces rdfs:label "produces - holds between a material entity and a product that is generated through the intentional actions or functioning of the material entity" .
  biolink:provided_by rdfs:label "provided by - The value in this node property represents the knowledge provider that created or assembled the node and all of its attributes. Used internally to represent how a particular node made its way into a knowledge provider or graph." .
  biolink:provider rdfs:label "provider - person, group, organization or project that provides a piece of information (e.g. a knowledge association)." .
  biolink:publication_id rdfs:label "publication id - Different kinds of publication subtypes will have different preferred identifiers (curies when feasible). Precedence of identifiers for scientific articles is as follows: PMID if available; DOI if not; actual alternate CURIE otherwise. Enclosing publications (i.e. referenced by 'published in' node property) such as books and journals, should have industry-standard identifier such as from ISBN and ISSN." .
  biolink:publication_name rdfs:label "publication name - the 'title' of the publication is generally recorded in the 'name' property (inherited from NamedThing). The field name 'title' is now also tagged as an acceptable alias for the node property 'name' (just in case)." .
  biolink:publication_pages rdfs:label "publication pages - When a 2-tuple of page numbers are provided, they represent the start and end page of the publication within its parent publication context. For books, this may be set to the total number of pages of the book." .
  biolink:publication_publication_type rdfs:label "publication publication type - Ontology term for publication type may be drawn from Dublin Core types (https://www.dublincore.org/specifications/dublin-core/dcmi-type-vocabulary/), FRBR-aligned Bibliographic Ontology (https://sparontologies.github.io/fabio/current/fabio.html), the MESH publication types (https://www.nlm.nih.gov/mesh/pubtypes.html), the Confederation of Open Access Repositories (COAR) Controlled Vocabulary for Resource Type Genres (http://vocabularies.coar-repositories.org/documentation/resource_types/), Wikidata (https://www.wikidata.org/wiki/Wikidata:Publication_types), or equivalent publication type ontology. When a given publication type ontology term is used within a given knowledge graph, then the CURIE identified term must be documented in the graph as a concept node of biolink:category biolink:OntologyClass." .
  biolink:publication_type rdfs:label "publication type - Ontology term for publication type may be drawn from Dublin Core types (https://www.dublincore.org/specifications/dublin-core/dcmi-type-vocabulary/), FRBR-aligned Bibliographic Ontology (https://sparontologies.github.io/fabio/current/fabio.html), the MESH publication types (https://www.nlm.nih.gov/mesh/pubtypes.html), the Confederation of Open Access Repositories (COAR) Controlled Vocabulary for Resource Type Genres (http://vocabularies.coar-repositories.org/documentation/resource_types/), Wikidata (https://www.wikidata.org/wiki/Wikidata:Publication_types), or equivalent publication type ontology. When a given publication type ontology term is used within a given knowledge graph, then the CURIE identified term must be documented in the graph as a concept node of biolink:category biolink:OntologyClass." .
  biolink:publications rdfs:label "publications - One or more publications that report the statement expressed in an Association, or provide information used as evidence supporting this statement." .
  biolink:published_in rdfs:label "published in - CURIE identifier of a broader publication context within which the publication may be placed, e.g. a specified book or journal." .
  biolink:publisher rdfs:label "publisher - organization or person responsible for publishing books, periodicals, podcasts, games or software. Note that in the case of publications which have a containing \"published in\" node property, the publisher association may not be attached directly to the embedded child publication, but only made in between the parent's publication node and the publisher agent of the encompassing publication (e.g. only from the Journal referenced by the 'published_in' property of an journal article Publication node)." .
  biolink:qualified_predicate rdfs:label "qualified predicate - Predicate to be used in an association when subject and object qualifiers are present and the full reading of the statement requires a qualification to the predicate in use in order to refine or increase the specificity of the full statement reading. This qualifier holds a relationship to be used instead of that expressed by the primary predicate, in a ‘full statement’ reading of the association, where qualifier-based semantics are included. This is necessary only in cases where the primary predicate does not work in a full statement reading." .
  biolink:qualifier rdfs:label "qualifier - grouping slot for all qualifiers on an edge. useful for testing compliance with association classes" .
  biolink:qualifiers rdfs:label "qualifiers - connects an association to qualifiers that modify or qualify the meaning of that association" .
  biolink:quantifier_qualifier rdfs:label "quantifier qualifier - A measurable quantity for the object of the association" .
  biolink:reaction_direction rdfs:label "reaction direction - the direction of a reaction as constrained by the direction enum (ie: left_to_right, neutral, etc.)" .
  biolink:reaction_side rdfs:label "reaction side - the side of a reaction being modeled (ie: left or right)" .
  biolink:reaction_to_catalyst_association_object rdfs:label "reaction to catalyst association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:reaction_to_participant_association_subject rdfs:label "reaction to participant association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:regulates rdfs:label "regulates - A more specific form of affects, that implies the effect results from a biologically evolved control mechanism. Gene-affects-gene relationships will (almost) always involve regulation. Exogenous/environmental chemical-affects-gene relationships are not cases of regulation in this definition. Instead these would be captured using the 'affects' predicate, or possibly one of the 'interacts with' predicates depending on the nature of the interaction." .
  biolink:related_to rdfs:label "related to - A relationship that is asserted between two named things" .
  biolink:related_to_at_concept_level rdfs:label "related to at concept level - Represents a relationship held between terminology components that describe the conceptual model of a domain." .
  biolink:related_to_at_instance_level rdfs:label "related to at instance level - Represents a relationship held between two instances of a data classes. Much like an assertion component, in an ABox, these represent facts associated with the conceptual model." .
  biolink:relative_frequency_object rdfs:label "relative frequency object - The frequency at which subject and object concepts co-occur in records within a dataset/cohort, relative to the frequency at which the object concept appears in these same records." .
  biolink:relative_frequency_object_confidence_interval rdfs:label "relative frequency object confidence interval - The 99% confidence interval for the relative_frequency_object calculation (i.e. the range of values within which the true value has a 99% chance of falling)" .
  biolink:relative_frequency_subject rdfs:label "relative frequency subject - The frequency at which subject and object concepts co-occur in records within a dataset/cohort, relative to the frequency at which the subject concept appears in these same records." .
  biolink:relative_frequency_subject_confidence_interval rdfs:label "relative frequency subject confidence interval - The 99% confidence interval for the relative_frequency_subject calculation (i.e. the range of values within which the true value has a 99% chance of falling)" .
  biolink:resource rdfs:label "resource - The CURIE for an Information Resource that served as a source of knowledge expressed in an Edge, or a source of data used to generate this knowledge." .
  biolink:resource_role rdfs:label "resource role - The role played by the InformationResource in serving as a source for an Edge. Note that a given Edge should have one and only one 'primary' source, and may have any number of 'aggregator' or 'supporting data' sources." .
  biolink:response_affected_by rdfs:label "response affected by - holds between two chemical entities where the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) of one is affected by the action of the other." .
  biolink:retrieval_source_resource rdfs:label "retrieval source resource - The InformationResource that served as a source for the knowledge expressed in an Edge, or data used to generate this knowledge." .
  biolink:retrieval_source_resource_role rdfs:label "retrieval source resource role - The role of the InformationResource in the retrieval of the knowledge expressed in an Edge, or data used to generate this knowledge." .
  biolink:retrieval_source_upstream_resources rdfs:label "retrieval source upstream resources - The InformationResources that served as a source for the InformationResource that served as a source for the knowledge expressed in an Edge, or data used to generate this knowledge." .
  biolink:routes_of_delivery rdfs:label "routes of delivery - the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals." .
  biolink:same_as rdfs:label "same as - holds between two entities that are considered equivalent to each other" .
  biolink:sequence_feature_relationship_object rdfs:label "sequence feature relationship object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:sequence_feature_relationship_subject rdfs:label "sequence feature relationship subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:sequence_localization_attribute rdfs:label "sequence localization attribute - An attribute that can be applied to a genome sequence localization edge. These edges connect a nucleic acid entity such as an exon to an entity such as a chromosome. Edge properties are used to ascribe specific positional information and other metadata to the localization. In pragmatic terms this can be thought of as columns in a GFF3 line." .
  biolink:sequence_variant_has_biological_sequence rdfs:label "sequence variant has biological sequence - The state of the sequence w.r.t a reference sequence" .
  biolink:sequence_variant_has_gene rdfs:label "sequence variant has gene - Each allele can be associated with any number of genes" .
  biolink:sequence_variant_id rdfs:label "sequence variant id - A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI" .
  biolink:sequence_variant_modulates_treatment_association_object rdfs:label "sequence variant modulates treatment association object - treatment whose efficacy is modulated by the subject variant" .
  biolink:sequence_variant_modulates_treatment_association_subject rdfs:label "sequence variant modulates treatment association subject - variant that modulates the treatment of some disease" .
  biolink:sequence_variant_qualifier rdfs:label "sequence variant qualifier - a qualifier used in an association with the variant" .
  biolink:serial_id rdfs:label "serial id - Serials (journals) should have industry-standard identifier such as from ISSN." .
  biolink:serial_type rdfs:label "serial type - Should generally be set to an ontology class defined term for 'serial' or 'journal'." .
  biolink:severity_qualifier rdfs:label "severity qualifier - a qualifier used in a phenotypic association to state how severe the phenotype is in the subject" .
  biolink:sex_qualifier rdfs:label "sex qualifier - a qualifier used in a phenotypic association to state whether the association is specific to a particular sex." .
  biolink:similar_to rdfs:label "similar to - holds between an entity and some other entity with similar features." .
  biolink:small_molecule_id rdfs:label "small molecule id - A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI" .
  biolink:socioeconomic_exposure_has_attribute rdfs:label "socioeconomic exposure has attribute - connects any entity to an attribute" .
  biolink:species_context_qualifier rdfs:label "species context qualifier - A statement qualifier representing a taxonomic category of species in which a relationship expressed in an association took place." .
  biolink:stage_qualifier rdfs:label "stage qualifier - stage during which gene or protein expression of takes place." .
  biolink:start_coordinate rdfs:label "start coordinate - The position at which the subject genomic entity starts on the chromosome or other entity to which it is located on. (ie: the start of the sequence being referenced is 1)." .
  biolink:start_interbase_coordinate rdfs:label "start interbase coordinate - The position at which the subject nucleic acid entity starts on the chromosome or other entity to which it is located on. (ie: the start of the sequence being referenced is 0)." .
  biolink:statement_qualifier rdfs:label "statement qualifier - " .
  biolink:stoichiometry rdfs:label "stoichiometry - the relationship between the relative quantities of substances taking part in a reaction or forming a compound, typically a ratio of whole integers." .
  biolink:strand rdfs:label "strand - The strand on which a feature is located. Has a value of '+' (sense strand or forward strand) or '-' (anti-sense strand or reverse strand)." .
  biolink:subclass_of rdfs:label "subclass of - holds between two classes where the domain class is a specialization of the range class" .
  biolink:subject rdfs:label "subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:subject_location_in_text rdfs:label "subject location in text - Character offsets for the text span(s) in the supporting text corresponding to the subject concept of the extracted assertion." .
  biolink:summary rdfs:label "summary - executive summary of a publication" .
  biolink:superclass_of rdfs:label "superclass of - holds between two classes where the domain class is a super class of the range class" .
  biolink:support_graphs rdfs:label "support graphs - A list of knowledge graphs that support the existence of this node." .
  biolink:supporting_data_set rdfs:label "supporting data set - A set of data used as evidence to generate the knowledge expressed in an Association (e.g. through computation on, reasoning or inference over the retrieved data)." .
  biolink:supporting_data_source rdfs:label "supporting data source - An Information Resource from which data was retrieved and subsequently used as evidence to generate the knowledge expressed in an Association (e.g. through computation on, reasoning or inference over the retrieved data)." .
  biolink:supporting_document_type rdfs:label "supporting document type - The document type (e.g., Journal Article, Case Study, Preprint) for the supporting document used in a Text Mining Result." .
  biolink:supporting_document_year rdfs:label "supporting document year - The document year (typically the publication year) for the supporting document used in a Text Mining Result." .
  biolink:supporting_documents rdfs:label "supporting documents - One or more referencable documents that report the statement expressed in an Association, or provide information used as evidence supporting this statement." .
  biolink:supporting_study_cohort rdfs:label "supporting study cohort - A description of a study population/cohort that was interrogated to provide evidence for the association (e.g. the inclusion and exclusion criteria)." .
  biolink:supporting_study_context rdfs:label "supporting study context - A term or terms describing the experimental setting/context in which evidence supporting the Association was generated ('context' may be defined by many factors, including taxon, model system (e.g. cell line type), tissue type, disease, etc.)." .
  biolink:supporting_study_date_range rdfs:label "supporting study date range - The date range over which data was collected in a study that provided evidence for an Association." .
  biolink:supporting_study_metadata rdfs:label "supporting study metadata - Information about a study used to generate information used as evidence to support the knowledge expressed in an Association. In practice, data creators should use one of the more specific subtypes of this property." .
  biolink:supporting_study_method_description rdfs:label "supporting study method description - A uri or curie pointing to information about the methodology used to generate data supporting an Association." .
  biolink:supporting_study_method_type rdfs:label "supporting study method type - A type of method that was applied in a study used to generate the information used as evidence (e.g. a type of experimental assay, or statistical calculation, or computational analysis)." .
  biolink:supporting_study_size rdfs:label "supporting study size - The sample size used in a study that provided evidence for the association (e.g. 'n' of a cohort for a clinical study)." .
  biolink:supporting_text rdfs:label "supporting text - The segment of text from a document that supports the mined assertion." .
  biolink:supporting_text_section_type rdfs:label "supporting text section type - The section of the supporting text of a Text Mining Result within the supporting document. This is in the form of the name of the document section (e.g., Abstract, Introduction) that contains the supporting text." .
  biolink:symbol rdfs:label "symbol - Symbol for a particular thing" .
  biolink:synonym rdfs:label "synonym - Alternate human-readable names for a thing" .
  biolink:systematic_synonym rdfs:label "systematic synonym - more commonly used for gene symbols in yeast" .
  biolink:target_for rdfs:label "target for - A gene is a target of a disease when its products are druggable and when a drug interaction with the gene product could have a therapeutic effect" .
  biolink:taxon_to_taxon_association_object rdfs:label "taxon to taxon association object - An association between individuals of different taxa." .
  biolink:taxon_to_taxon_association_subject rdfs:label "taxon to taxon association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:temporal_context_qualifier rdfs:label "temporal context qualifier - a constraint of time placed upon the truth value of an association. for time intervales, use temporal interval qualifier." .
  biolink:temporal_interval_qualifier rdfs:label "temporal interval qualifier - a constraint of a time interval placed upon the truth value of an association." .
  biolink:temporally_related_to rdfs:label "temporally related to - holds between two entities with a temporal relationship" .
  biolink:timepoint rdfs:label "timepoint - a point in time" .
  biolink:trade_name rdfs:label "trade name - " .
  biolink:transcribed_from rdfs:label "transcribed from - x is transcribed from y if and only if x is synthesized from template y" .
  biolink:transcribed_to rdfs:label "transcribed to - inverse of transcribed from" .
  biolink:transcript_to_gene_relationship_object rdfs:label "transcript to gene relationship object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:transcript_to_gene_relationship_subject rdfs:label "transcript to gene relationship subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:translates_to rdfs:label "translates to - x (amino acid chain/polypeptide) is the ribosomal translation of y (transcript) if and only if a ribosome reads y (transcript) through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces x (amino acid chain/polypeptide)" .
  biolink:translation_of rdfs:label "translation of - inverse of translates to" .
  biolink:treated_by rdfs:label "treated by - holds between a disease or phenotypic feature and a therapeutic process or chemical entity that is used to treat the condition" .
  biolink:treats rdfs:label "treats - holds between a therapeutic procedure or chemical entity and a disease or phenotypic feature that it is used to treat" .
  biolink:update_date rdfs:label "update date - date on which an entity was updated. This can be applied to nodes or edges" .
  biolink:upstream_resources rdfs:label "upstream resources - An upstream InformationResource from which the resource being described directly retrieved a record of the knowledge expressed in the Edge, or data used to generate this knowledge. This is an array because there are cases where a merged Edge holds knowledge that was retrieved from multiple sources. e.g. an Edge provided by the ARAGORN ARA can expressing knowledge it retrieved from both the automat-mychem-info and molepro KPs, which both provided it with records of this single fact." .
  biolink:variant_as_a_model_of_disease_association_subject rdfs:label "variant as a model of disease association subject - A variant that has a role in modeling the disease." .
  biolink:variant_to_disease_association_object rdfs:label "variant to disease association object - a disease that is associated with that variant" .
  biolink:variant_to_disease_association_predicate rdfs:label "variant to disease association predicate - E.g. is pathogenic for" .
  biolink:variant_to_disease_association_subject rdfs:label "variant to disease association subject - a sequence variant in which the allele state is associated in some way with the disease state" .
  biolink:variant_to_entity_association_mixin_subject rdfs:label "variant to entity association mixin subject - a sequence variant in which the allele state is associated with some other entity" .
  biolink:variant_to_gene_association_object rdfs:label "variant to gene association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object." .
  biolink:variant_to_gene_association_predicate rdfs:label "variant to gene association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:variant_to_gene_expression_association_predicate rdfs:label "variant to gene expression association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes." .
  biolink:variant_to_phenotypic_feature_association_subject rdfs:label "variant to phenotypic feature association subject - a sequence variant in which the allele state is associated in some way with the phenotype state" .
  biolink:variant_to_population_association_has_count rdfs:label "variant to population association has count - number in object population that carry a particular allele, aka allele count" .
  biolink:variant_to_population_association_has_quotient rdfs:label "variant to population association has quotient - frequency of allele in population, expressed as a number with allele divided by number in reference population, aka allele frequency" .
  biolink:variant_to_population_association_has_total rdfs:label "variant to population association has total - number all populations that carry a particular allele, aka allele number" .
  biolink:variant_to_population_association_object rdfs:label "variant to population association object - the population that is observed to have the frequency" .
  biolink:variant_to_population_association_subject rdfs:label "variant to population association subject - an allele that has a certain frequency in a given population" .
  biolink:volume rdfs:label "volume - volume of a book or music release in a collection/series or a published collection of journal issues in a serial publication" .
  biolink:xenologous_to rdfs:label "xenologous to - a homology relationship characterized by an interspecies (horizontal) transfer since the common ancestor." .
  biolink:xref rdfs:label "xref - Alternate CURIEs for a thing" .
}
sub:provenance {
  sub:assertion prov:wasDerivedFrom <https://raw.githubusercontent.com/biolink/biolink-model/master/biolink-model.ttl> .
}
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}