@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix ns1: <https://w3id.org/np/o/ntemplate/> .
@prefix this: <http://purl.org/np/RAuzcTL7DgSx9wcGJhHgKR6_vV_N9yyvgq7bq-_xpTMVc> .
@prefix sub: <http://purl.org/np/RAuzcTL7DgSx9wcGJhHgKR6_vV_N9yyvgq7bq-_xpTMVc#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_13884> biolink:category biolink:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_13884>;
    rdf:predicate biolink:treats;
    rdf:subject <https://identifiers.org/drugbank:DB00661>;
    a rdf:Statement;
    rdfs:label "\"Verapamil is contraindicated in:   Severe left ventricular dysfunction [ see  Warnings and Precautions (5.1) Hypotension (less than 90 mm Hg systolic pressure) or cardiogenic shock. Sick sinus syndrome (except in patients with a functioning artificial ventricular pacemaker). Second- or third-degree AV block (except in patients with a functioning artificial ventricular pacemaker). Patients with atrial flutter or atrial fibrillation and an accessory bypass tract (e.g., Wolff-Parkinson-White, Lown-Ganong-Levine syndromes) [ see  Warnings and Precautions (5.4)   Severe left ventricular dysfunction ( 4 Hypotension (<90 mmHg systolic pressure) or cardiogenic shock ( 4 Sick sinus syndrome (except in patients with pacemaker) ( 4 2nd- or 3rd-degree AV block (except in patients with pacemaker) ( 4 Atrial flutter or atrial fibrillation and an accessory bypass tract ( 4\"";
    biolink:provided_by <https://w3id.org/um/NeuroDKG>;
    biolink:relation schema:MedicalContraindication .
  
  <https://identifiers.org/drugbank:DB00661> biolink:category biolink:Drug .
}

sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "EDTW1e4M6G6juFaCkiAB9vmQ6g24/FAOlag/ammU9HAITXTCuLRk0YZ9+FYLfsOQsjzywFkBeeI83GrUmBdMfU/Mwx60KyanqOB4fcbLmNNpzbSs+ess6YXduR8/Z7FqrXrqcWW9kVUBB5YXrngQND3Z2sXcsivwalfvtha0YMY=";
    npx:hasSignatureTarget this: .
  
  this: dct:created "2021-08-23T12:38:41.286+02:00"^^xsd:dateTime;
    dct:creator orcid:0000-0002-1468-3557;
    ns1:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    ns1:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    ns1:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
}