@prefix np: <http://www.nanopub.org/nschema#> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix ns1: <https://w3id.org/np/RALUzHtS1E_Mba_zwMhhENjZgd23vM0IivF-tUBC633dI#> .
@prefix ns2: <https://w3id.org/np/RALUzHtS1E_Mba_zwMhhENjZgd23vM0IivF-tUBC633dI#hasMeasurement&> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix sub: <http://purl.org/np/RAxTu7VCHe-QnO1W-QIrv-UYw8kx3krWsDrPC9RWaZ2F8#> .
@prefix this: <http://purl.org/np/RAxTu7VCHe-QnO1W-QIrv-UYw8kx3krWsDrPC9RWaZ2F8> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  ns1:BiologicalContext ns1:hasBiologicalOrganizationLevel "Community";
    ns1:hasOrganTerm "heart" .
  
  ns1:Components ns1:hasAction "Decreased";
    ns1:hasObject "thyroxine";
    ns1:hasProcess "abnormal circulating thyroxine level" .
  
  ns1:IncludedInAOP ns1:hasAOPName "TPO Inhibition and Altered Neurodevelopment";
    ns1:hasAuthorStatus "Open for citation & comment";
    ns1:hasOECDStatus "WPHA/WNT Endorsed";
    ns1:hasPointOfContact "Kevin Crofton";
    ns1:hasRoleInAOP "KeyEvent" .
  
  ns1:KeyEvent ns1:hasApplicabilityDomain "appdom";
    ns1:hasBiologicalContext ns1:BiologicalContext;
    ns1:hasComponents ns1:Components;
    ns1:hasDescription "desc";
    ns1:hasID "12132";
    ns2:DetectionTechniques "madtech";
    ns1:hasOverview ns1:Overview;
    ns1:hasReferences ns1:References;
    ns1:hasShortName "name short";
    ns1:hasTitle "title" .
  
  ns1:LifeStages ns1:hasLifeStage "All life stages";
    ns1:hasLifeStagesEvidence "High" .
  
  ns1:Overview ns1:hasIncludedInAOP ns1:IncludedInAOP;
    ns1:hasLifeStages ns1:LifeStages;
    ns1:hasSexApplicability ns1:SexApplicability;
    ns1:hasTaxonomicApplicability ns1:TaxonomicApplicability .
  
  ns1:References ns1:hasDOI "10.1080/15287390590912153";
    ns1:hasTitle "Risk assessment for benefits analysis: framework for analysis of a thyroid-disrupting chemical" .
  
  ns1:SexApplicability ns1:hasSex "Female";
    ns1:hasSexApplicabilityEvidence "High" .
  
  ns1:TaxonomicApplicability ns1:hasScientificTerm "Gallus gallus";
    ns1:hasTaxonomicApplicabilityEvidence "Moderate";
    ns1:hasTerm "chicken" .
}

sub:provenance {
  sub:assertion prov:generatedAtTime "2024-09-21T10:31:16.914021"^^xsd:dateTime .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey """MIIBIjANBgkqhkiG9w0BAQEFAAOCAQ8AMIIBCgKCAQEAzaQ1+ecbf7L6nE0aWb+m
YlO/ykQJJGWM0HLetmJzF+mXsVE7zK06PUF5FErmEIQKnx0x0OafORHJ5bG1q5c9
njIL/tEqiESJk7azHgiKq4zNUNW/1NBsm2EtrYIqMhUkqUC8+pvRYxzDaCXLNkAR
yAu5n+EsJRLrd1+BmKJu1D0skcYYdpl4WQhBCA8CNZNpvApy+7Rx/h5X3Dzp4dxC
W0Q9LcBBPd69QwZ+BOBztGj9/iusdJWXfQcM7xiXSaRb8BqQrmfV3YJCKj+oxOiE
7kG0/lzyNpq869clikK0MTcyoq/l+9zbRctZKB0SXoXZjeEdJzLo3/xiODxtElQG
fwIDAQAB""";
    npx:hasSignature "Qy7L6w7yRrC0QRszwGhJHhsn/tkWTKAzLnEQ622/k/VGtW3XYYs8PaVbVeLCRqchex7yuAS68X2ge755oodR2VUIl15n26icdH1+T5jBtj9b/lH7pldwH3aofqChanBOZ9LwGSPUSIBC478AqHXFjnU3saqFblvTLH93YcFLvDcN7nChCXH6CJa0Vo5nk+GWL9JheGHsrgZyr+eykijmpJ8/XK/zIG2RUxqRur18pxe56toyMII9xt6Tp60t5fqgBiU6zfCxv663as/3t6TU/gjFHLD0exiuv+a/zHkq8jSfyjwTtitT1pHzzWcfW9TkoZ0hlZhLGRVzU6iz7CDelA==";
    npx:hasSignatureTarget this: .
  
  this: prov:wasAttributedTo orcid:0009-0008-1416-1055 .
}