sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_8986> bl:category bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_8986> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://identifiers.org/drugbank:DB00422> ;
    a rdf:Statement ;
    rdfs:label "attention deficit disorders narcolepsy attention deficit disorders methylphenidate hydrochloride chewable tablets are indicated as an integral part of a total treatment program which typically includes other remedial measures psychological educational social for a stabilizing effect in children with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms moderate to severe distractibility short attention span hyperactivity emotional lability and impulsivity the diagnosis of this syndrome should not be made with finality when these symptoms are only of comparatively recent origin nonlocalizing soft neurological signs learning disability and abnormal eeg may or may not be present and a diagnosis of central nervous system dysfunction may or may not be warranted special diagnostic considerations specific etiology of this syndrome is unknown and there is no single diagnostic test adequate diagnosis requires the use not only of medical but of special psychological educational and social resources characteristics commonly reported include chronic history of short attention span distractibility emotional lability impulsivity and moderate to severe hyperactivity minor neurological signs and abnormal eeg learning may or may not be impaired the diagnosis must be based upon a complete history and evaluation of the child and not solely on the presence of one or more of these characteristics drug treatment is not indicated for all children with this syndrome stimulants are not intended for use in the child who exhibits symptoms secondary to environmental factors and or primary psychiatric disorders including psychosis appropriate educational placement is essential and psychosocial intervention is generally necessary when remedial measures alone are insufficient the decision to prescribe stimulant medication will depend upon the physician s assessment of the chronicity and severity of the child s symptoms" ;
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:relation schema:TreatmentIndication .
  <https://identifiers.org/drugbank:DB00422> bl:category bl:Drug .
}