sub:assertion {
<
http://purl.obolibrary.org/obo/DOID_5844>
biolink:category biolink:Disease .
sub:association rdf:object <
http://purl.obolibrary.org/obo/DOID_5844> ;
rdf:predicate biolink:treats ;
rdf:subject <
https://identifiers.org/drugbank:DB01079> ;
a rdf:Statement ;
rdfs:label "\"ZELNORM is contraindicated in patients with: A history of myocardial infarction (MI), stroke, transient ischemic attack (TIA), or angina [see Warnings and Precautions (5.1) A history of ischemic colitis or other forms of intestinal ischemia [see Warnings and Precautions (5.2) Severe renal impairment (eGFR< 15 mL/min/1.73 m 2 [see Use in Specific Populations (8.6) Moderate and severe hepatic impairment (Child-Pugh B or C) [see Use in Specific Populations (8.7) A history of bowel obstruction, symptomatic gallbladder disease, suspected sphincter of Oddi dysfunction, or abdominal adhesions [see Adverse Reactions (6.2) Hypersensitivity to tegaserod [see Adverse Reactions (6.2) ZELNORM is contraindicated in patients with: A history of myocardial infarction, stroke, transient ischemic attack, or angina. ( 4 5.1 A history of ischemic colitis or other forms of intestinal ischemia. ( 4 5.2 Severe renal impairment (eGFR< 15 mL/min/1.73 m 2 4 8.6 Moderate or severe hepatic impairment (Child-Pugh B or C). ( 4 8.7 A history of bowel obstruction, symptomatic gallbladder disease, suspected sphincter of Oddi dysfunction, or abdominal adhesions. ( 4 Hypersensitivity to tegaserod. ( 4\"" ;
biolink:provided_by <
https://w3id.org/um/NeuroDKG> ;
biolink:relation schema:MedicalContraindication .
<
https://identifiers.org/drugbank:DB01079>
biolink:category biolink:Drug .
}