http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#head http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#assertion http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#provenance http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#assertion http://rdf.disgenet.org/resource/gda/DGNc2518619f0363659ec6c17cb57f06c9d http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/80332 http://rdf.disgenet.org/resource/gda/DGNc2518619f0363659ec6c17cb57f06c9d http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0004096 http://rdf.disgenet.org/resource/gda/DGNc2518619f0363659ec6c17cb57f06c9d http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001122 http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#provenance http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#assertion http://purl.org/dc/terms/description [Because genetic studies have shown that ADAM-33 gene polymorphisms are associated with asthma, we designed this study to assess mRNA expression profile of several ADAM and ADAMTS proteases in sputum from patients with asthma and to investigate the relationship between expression of these proteases and asthma-associated inflammation and airway obstruction. mRNA expression profile of selected ADAM and ADAMTS proteinases (ADAM-8, -9, -10, -12, -15, -17, and -33; ADAMTS-1, -2, -15, -16, -17, -18, and -19), their physiological inhibitors TIMP-1 and TIMP-3, and RECK, a membrane-anchored MMP activity regulator, was obtained by RT-PCR analysis performed on cells collected by sputum induction from 21 patients with mild to moderate asthma and 17 healthy individuals. mRNA levels of ADAM-8, ADAM-9, ADAM-12, TIMP-1, and TIMP-3 were significantly increased, whereas mRNA levels coding for ADAMTS-1, ADAMTS-15, and RECK were significantly decreased in patients with asthma compared with control patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/17088949 http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v5.0.0/void/BEFREE http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v5.0.0/void/BEFREE http://purl.org/pav/importedOn 2017-02-19 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/dc/terms/created 2017-10-17T13:18:55+02:00 http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v5.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1375772.RA40PnNNE4Orc4ph0suPLx3U7lbcRuWAUkaWQJgrhQSo4 http://purl.org/pav/version v5.0.0.0 http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v5.0.0