@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix ns1: <http://www.w3.org/ns/prov#> .
@prefix this: <http://purl.org/np/RA4CzbLvHQhOLa60VQQNlWwSdKV84nCDXKBsOK0wJtM24> .
@prefix sub: <http://purl.org/np/RA4CzbLvHQhOLa60VQQNlWwSdKV84nCDXKBsOK0wJtM24#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   <http://purl.obolibrary.org/obo/DOID_1459> bl:category bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_1459> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://identifiers.org/drugbank:DB00279> ;
    a rdf:Statement ;
    rdfs:label "liothyronine sodium is an l triiodothyronine t3 indicated for hypothyroidism as replacement in primary thyroidal secondary pituitary and tertiary hypothalamic congenital or acquired hypothyroidism 1 1 pituitary thyroid stimulating hormone tsh suppression as an adjunct to surgery and radioiodine therapy in the management of well differentiated thyroid cancer 1 2 thyroid suppression test as a diagnostic agent in suppression tests to differentiate suspected mild hyperthyroidism or thyroid gland autonomy 1 3 limitations of use not indicated for suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine sufficient patients 1 not indicated for treatment of hypothyroidism during the recovery phase of subacute thyroiditis 1 liothyronine sodium is indicated as a replacement therapy in primary thyroidal secondary pituitary and tertiary hypothalamic congenital or acquired hypothyroidism liothyronine sodium is indicated as an adjunct to surgery and radioiodine therapy in the management of well differentiated thyroid cancer liothyronine sodium is indicated as a diagnostic agent in suppression tests to differentiate suspected mild hyperthyroidism or thyroid gland autonomy limitations of use liothyronine sodium is not indicated for suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine sufficient patients as there are no clinical benefits and overtreatment with liothyronine sodium may induce hyperthyroidism see warnings and precautions 5 4 liothyronine sodium is not indicated for treatment of hypothyroidism during the recovery phase of subacute thyroiditis" ;
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:relation schema:TreatmentIndication .
  <https://identifiers.org/drugbank:DB00279> bl:category bl:Drug .
}
sub:provenance {
   sub:assertion ns1:wasAttributedTo orcid:0000-0002-1468-3557 .
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sub:pubinfo {
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    npx:hasSignatureTarget this: .
  this: dcterms:created "2021-06-30T09:22:55.255+02:00"^^xsd:dateTime ;
    dcterms:creator orcid:0000-0002-1468-3557 ;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM> ;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM> ;
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}