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[When we evaluated these two tSNPs together based on the risk alleles (that is, rs6434568 C and rs16834898 A), we found that the combined genotypes with four risk alleles were associated with an increased risk of PCa compared with those carrying 0-3 risk alleles (1.53, 1.19-1.97), and this increased risk was more pronounced among subjects of?70 years (1.80, 1.24-2.62), Gleason score?7 (1.68, 1.28-2.22) and PSA level?20 (1.64, 1.24-2.18).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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