@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_head {
  this: np:hasAssertion dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_assertion;
    np:hasProvenance dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_provenance;
    np:hasPublicationInfo dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_assertion a np:Assertion .
  
  dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_provenance a np:Provenance .
  
  dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_assertion {
  miriam-gene:1559 a ncit:C16612 .
  
  lld:C2608079 a ncit:C7057 .
  
  dgn-gda:DGN8b5b66d1eb9660557345e9524e8d81e0 sio:SIO_000628 miriam-gene:1559, lld:C2608079;
    a sio:SIO_001122 .
}

dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_provenance {
  dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_assertion dcterms:description
      "[In this study population of patients with severe comorbid conditions and those treated with medications that potentially interact with warfarin, CYP2C9 *1/*3 genotype, older age, CHF, and the use of antibiotics were associated with lower warfarin dosage requirements. The CYP2C9*1/*3 genotype, compared with CYP2C9 *1/*1, was associated with 33% lower mean warfarin dosage requirements and higher INR values, which were higher than the upper therapeutic range of INR (ie, 3). Genetic CYP2C9 polymorphism contributed to the variability in warfarin dosage requirements in the presence of drug-disease and drug-drug interactions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:17577464;
    prov:wasDerivedFrom dgn-void:gad-20130706;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:gad-20130706 pav:importedOn "2013-07-06"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP45761.RA6QsoJyfJ55g7YgEWSwL_VhWc42eODso1MM8nd7qzycA130_publicationInfo {
  this: dcterms:created "2014-10-02T12:32:21+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}