@prefix dc1: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://purl.org/np/RA9OlXFdM2XuinwH5A1gY03jTUstU4suHJcKEam7qm95c
> .
@prefix sub: <
http://purl.org/np/RA9OlXFdM2XuinwH5A1gY03jTUstU4suHJcKEam7qm95c#
> .
@prefix schema: <
https://schema.org/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix nt: <
https://w3id.org/np/o/ntemplate/
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix bl: <
https://w3id.org/biolink/vocab/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/DOID_4450
>
bl:category
bl:Disease
.
sub:association
rdf:object
<
http://purl.obolibrary.org/obo/DOID_4450
> ;
rdf:predicate
bl:treats
;
rdf:subject
<
https://identifiers.org/drugbank:DB09078
> ;
a
rdf:Statement
;
rdfs:label
"lenvima is a kinase inhibitor that is indicated for the treatment of patients with locally recurrent or metastatic progressive radioactive iodine refractory differentiated thyroid cancer dtc 1 1 in combination with everolimus for the treatment of patients with advanced renal cell carcinoma rcc following one prior anti angiogenic therapy 1 2 for the first line treatment of patients with unresectable hepatocellular carcinoma hcc 1 3 lenvima is indicated for the treatment of patients with locally recurrent or metastatic progressive radioactive iodine refractory differentiated thyroid cancer dtc lenvima is indicated in combination with everolimus for the treatment of patients with advanced renal cell carcinoma rcc following one prior anti angiogenic therapy lenvima is indicated for the first line treatment of patients with unresectable hepatocellular carcinoma hcc" ;
bl:association_type
bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
bl:provided_by
<
https://w3id.org/um/NeuroDKG
> ;
bl:relation
schema:TreatmentIndication
.
<
https://identifiers.org/drugbank:DB09078
>
bl:category
bl:Drug
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-1468-3557
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB" ;
npx:hasSignature
"dZisx9uGdzZltCSmanjlLwXJLyBZaMWkUM0aQkqzBAki/VxTGpTxUsdde6cY8VHCCko6pEs466/ZO0xHsGfbei7i1cie6ckagN5aVVvzzpTp14WoSoNZE+5sA/4F4FtVUp6L37uMSIDa/ikFwJ/AGT3c5X5XxgquG9OgYd6x2Hk=" ;
npx:hasSignatureTarget
this:
.
this:
dc1:created
"2021-06-12T12:16:45.381+02:00"^^
xsd:dateTime
;
dc1:creator
orcid:0000-0002-1468-3557
;
nt:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
nt:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
nt:wasCreatedFromTemplate
<
http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs
> .
}