sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_1947> bl:category bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_1947> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://identifiers.org/drugbank:DB00916> ;
    a rdf:Statement ;
    rdfs:label "symptomatic trichomoniasis metronidazole tablets usp are indicated for the treatment of t vaginalis infection in females and males when the presence of the trichomonad has been confirmed by appropriate laboratory procedures wet smears and or cultures asymptomatic trichomoniasis metronidazole tablets usp are indicated in the treatment of asymptomatic t vaginalis infection in females when the organism is associated with endocervicitis cervicitis or cervical erosion since there is evidence that presence of the trichomonad can interfere with accurate assessment of abnormal cytological smears additional smears should be performed after eradication of the parasite treatment of asymptomatic sexual partners t vaginalis infection is a venereal disease therefore asymptomatic sexual partners of treated patients should be treated simultaneously if the organism has been found to be present in order to prevent reinfection of the partner the decision as to whether to treat an asymptomatic male partner who has a negative culture or one for whom no culture has been attempted is an individual one in making this decision it should be noted that there is evidence that a woman may become reinfected if her sexual partner is not treated also since there can be considerable difficulty in isolating the organism from the asymptomatic male carrier negative smears and cultures cannot be relied upon in this regard in any event the sexual partner should be treated with metronidazole tablets usp in cases of reinfection amebiasis metronidazole tablets usp are indicated in the treatment of acute intestinal amebiasis amebic dysentery and amebic liver abscess in amebic liver abscess metronidazole tablet therapy does not obviate the need for aspiration or drainage of pus anaerobic bacterial infections metronidazole tablets usp are indicated in the treatment of serious infections caused by susceptible anaerobic bacteria indicated surgical procedures should be performed in conjunction with metronidazole tablet therapy in a mixed aerobic and anaerobic infection antimicrobials appropriate for the treatment of the aerobic infection should be used in addition to metronidazole tablets usp intra abdominal infections including peritonitis intra abdominal abscess and liver abscess caused by bacteroides species including the b fragilis group b fragilis b distasonis b ovatus b thetaiotaomicron b vulgatus clostridium species eubacterium species peptococcus species and peptostreptococcus species skin and skin structure infections caused by bacteroides species including the b fragilis group clostridium species peptococcus species peptostreptococcus species and fusobacterium species gynecologic infections including endometritis endomyometritis tubo ovarian abscess and postsurgical vaginal cuff infection caused by bacteroides species including the b fragilis group clostridium species peptococcus species peptostreptococcus species and fusobacterium species bacterial septicemia caused by bacteroides species including the b fragilis group and clostridium species bone and joint infections as adjunctive therapy caused by bacteroides species including the b fragilis group central nervous system cns infections including meningitis and brain abscess caused by bacteroides species including the b fragilis group lower respiratory tract infections including pneumonia empyema and lung abscess caused by bacteroides species including the b fragilis group endocarditis caused by bacteroides species including the b fragilis group to reduce the development of drug resistant bacteria and maintain the effectiveness of metronidazole tablets usp and other antibacterial drugs metronidazole tablets usp should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria when culture and susceptibility information are available they should be considered in selecting or modifying antibacterial therapy in the absence of such data local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy" ;
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:relation schema:TreatmentIndication .
  <https://identifiers.org/drugbank:DB00916> bl:category bl:Drug .
}