@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_head {
  this: np:hasAssertion dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_assertion;
    np:hasProvenance dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_provenance;
    np:hasPublicationInfo dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_assertion a np:Assertion .
  
  dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_provenance a np:Provenance .
  
  dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_assertion {
  miriam-gene:1437 a ncit:C16612 .
  
  lld:C1863340 a ncit:C7057 .
  
  dgn-gda:DGNcb90d198960042a7cec75186f0b19103 sio:SIO_000628 miriam-gene:1437, lld:C1863340;
    a sio:SIO_001121 .
}

dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_provenance {
  dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_assertion dcterms:description
      "[We have found that: 1) system y+L activity is markedly lowered in monocytes and alveolar macrophages from the LPI patient, because of the prevailing expression of SLC7A7/y+LAT1 in these cells; 2) on the contrary, fibroblasts isolated from the same patient do not display the transport defect due to compensation by the SLC7A6/y+LAT2 isoform; 3) in both normal and LPI monocytes, GM-CSF induces the expression of SLC7A7, suggesting that the gene is a target of the cytokine; 4) GM-CSF-induced differentiation of LPI monocytes is comparable to that of normal cells, demonstrating that GM-CSF signalling is unaltered; 5) general and respiratory conditions of the patient, along with PAP-associated parameters, markedly improved after GM-CSF therapy through aerosolization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:21110863;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP450412.RACDTzQqmnAjDIqeFolniAeM0-089wbhtcEgHgHwLMJ_Y130_publicationInfo {
  this: dcterms:created "2014-10-02T12:36:28+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}