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[In a screen for dominant mutations affecting cardiovascular function in N-ethyl-N-nitrosourea (ENU) mutagenized mice, we identified a missense mutation in the Klf3 gene that caused aortic valvular stenosis and partially penetrant perinatal lethality in heterozygotes.All homozygotes died as embryos.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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