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[We conclude that 1) the increased leptin in exacerbated UC is related to the increased serum proinflammatory cytokines IL-1?, TNF-? and IL-6 levels; 2) In patients with infectious diarrhea, the concentrations of leptin in intestinal mucosa correlates with serum concentrations of cytokines IL-1?, IL-6 and TNF-? and with an increased expression of leptin mRNA in intestinal mucosa but not with alterations in serum levels of this hormone; 3) leptin may serve as useful predictive marker of inflammation in inflammatory bowel disease (IBD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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