http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#Head http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#assertion http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#provenance http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#assertion http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_1 http://www.selventa.com/vocabulary/variantOf http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/AKT%20Family http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00696 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/UBERON_0002371 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_2 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_1 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/LY%20294002 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#assertion http://www.w3.org/2000/01/rdf-schema#label a(SCHEM:"LY 294002") -| p(SFAM:"AKT Family",pmod(P)) http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_4 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_3 http://www.w3.org/ns/prov#value Inhibition of PI3K resulted in a dose-dependent inhibition of RUNX2 activity with 30, 50, and 90% inhibition at LY294002 concentrations of 5, 10, and 20 µM, respectively. RUNX2 protein levels were also reduced, as was pAkt. http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15304489 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15304489 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#_3 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo http://purl.org/dc/terms/created 2014-07-03T14:32:27.001+02:00 http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAIf3Qo-RUNA7vMahm47uK-pKvqu6A1-EB7-2apS3KaHo http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234