. . . . "" . "Applied sciences" . . "service-account-enrichment" . . . . . . . . "11257"^^ . "https://api.rohub.org/api/ros/a8c21c10-47aa-4145-a2f2-173f1c501773/crate/download/" . . "2022-03-22 00:57:43.228000+00:00" . "2025-03-05 00:59:13.596088+00:00" . "2022-03-22 00:57:43.228000+00:00" . "To facilitate a more widespread use of volumetric tumor segmentation in clinical studies, there is an urgent need for reliable, user-friendly segmentation software. The aim of this study was therefore to compare three different software packages for semi-automatic brain tumor segmentation of glioblastoma; namely BrainVoyagerTM QX, ITK-Snap and 3D Slicer, and to make data available for future reference. Pre-operative, contrast enhanced T1-weighted 1.5 or 3 Tesla Magnetic Resonance Imaging (MRI) scans were obtained in 20 consecutive patients who underwent surgery for glioblastoma. MRI scans were segmented twice in each software package by two investigators. Intra-rater, inter-rater and between-software agreement was compared by using differences of means with 95 % limits of agreement (LoA), Dice’s similarity coefficients (DSC) and Hausdorff distance (HD). Time expenditure of segmentations was measured using a stopwatch. Eighteen tumors were included in the analyses. Inter-rater agreement was highest for BrainVoyager with difference of means of 0.19 mL and 95 % LoA from -2.42 mL to 2.81 mL. Between-software agreement and 95 % LoA were very similar for the different software packages. Intra-rater, inter-rater and between-software DSC were ≥ 0.93 in all analyses. Time expenditure was approximately 41 min per segmentation in BrainVoyager, and 18 min per segmentation in both 3D Slicer and ITK-Snap. Our main findings were that there is a high agreement within and between the software packages in terms of small intra-rater, inter-rater and between-software differences of means and high Dice’s similarity coefficients. Time expenditure was highest for BrainVoyager, but all software packages were relatively time-consuming, which may limit usability in an everyday clinical setting." . "application/ld+json" . . . . . "https://w3id.org/ro-id/a8c21c10-47aa-4145-a2f2-173f1c501773" . . "Glioblastoma Segmentation: Comparison of Three Different Software Packages" . "MANUAL" . "agreement" . "coefficient" . "comparison" . "concord" . "consumption" . "diversity" . "glioblastoma" . "magnetic resonance imaging" . "partition" . "rater" . "software" . "earth sciences" . "Computing and information technology" . "IT-computer sciences" . "Medical procedure-test" . "Software" . "Intra-" . "expenditure" . "glioblastoma" . "magnetic resonance imaging" . "rater" . "segmentation" . "software" . "mathematical and computer sciences" . "Hausdorff distance" . "differences of means" . "glioblastoma segmentation" . "software packages in terms" . "time expenditure" . "Between-software agreement and 95 % LoA were very similar for the different software packages." . "Our main findings were that there is a high agreement within and between the software packages in terms of small intra-rater, inter-rater and between-software differences of means and high Dice?s similarity coefficients." . "To facilitate a more widespread use of volumetric tumor segmentation in clinical studies, there is an urgent need for reliable, user-friendly segmentation software." . "18 min" . "approximately 41 min" . . . . . . "medicine" . "oncology" . "software" . "Even Fyllingen, Anne Line Stensjøen, Erik Magnus Berntsen, Ole Solheim, and Ingerid Reinertsen. \"Glioblastoma Segmentation: Comparison of Three Different Software Packages.\" ROHub. Mar 22 ,2022. https://w3id.org/ro-id/a8c21c10-47aa-4145-a2f2-173f1c501773." . "metadata" . . . "raw data" . . . . "data" . . . . "biblio" . . . "Fyllingen, E., Stensjøen, A. L., Berntsen, E. M., Solheim, O., Reinertsen, I. (2016).Glioblastoma Segmentation: Comparison of Three Different Software Packages [Data set]. Norstore. https://doi.org/10.11582/2016.00004" . "USIGT (USIGT)" . "Image" . . "https://archive.sigma2.no/pages/public/datasetDetail.jsf?id=10.11582/2016.00004" . . "2016-10-11 00:00:00" . "2022-03-22 00:58:14.814982+00:00" . "To facilitate a more widespread use of volumetric tumor segmentation in clinical studies, there is an urgent need for reliable, user-friendly segmentation software. The aim of this study was therefore to compare three different software packages for semi-automatic brain tumor segmentation of glioblastoma; namely BrainVoyagerTM QX, ITK-Snap and 3D Slicer, and to make data available for future reference. Pre-operative, contrast enhanced T1-weighted 1.5 or 3 Tesla Magnetic Resonance Imaging (MRI) scans were obtained in 20 consecutive patients who underwent surgery for glioblastoma. MRI scans were segmented twice in each software package by two investigators. Intra-rater, inter-rater and between-software agreement was compared by using differences of means with 95 % limits of agreement (LoA), Dice’s similarity coefficients (DSC) and Hausdorff distance (HD). Time expenditure of segmentations was measured using a stopwatch. Eighteen tumors were included in the analyses. Inter-rater agreement was highest for BrainVoyager with difference of means of 0.19 mL and 95 % LoA from -2.42 mL to 2.81 mL. Between-software agreement and 95 % LoA were very similar for the different software packages. Intra-rater, inter-rater and between-software DSC were ≥ 0.93 in all analyses. Time expenditure was approximately 41 min per segmentation in BrainVoyager, and 18 min per segmentation in both 3D Slicer and ITK-Snap. Our main findings were that there is a high agreement within and between the software packages in terms of small intra-rater, inter-rater and between-software differences of means and high Dice’s similarity coefficients. Time expenditure was highest for BrainVoyager, but all software packages were relatively time-consuming, which may limit usability in an everyday clinical setting." . . "Glioblastoma Segmentation: Comparison of Three Different Software Packages" . "2016-10-11 00:00:00" . . . . "Ingerid Reinertsen" . . "http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164891" . . "2022-03-22 00:58:11.962454+00:00" . "2022-03-22 00:58:12.066982+00:00" . . "http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164891" . "2022-03-22 00:58:11.962454+00:00" . . . . . . . "anne.line.stensjoen@rohub.com" . "Anne Line Stensjøen" . . "erik.magnus.berntsen@rohub.com" . "Erik Magnus Berntsen" . . "even.fyllingen@rohub.com" . "Even Fyllingen" . . "Geo H." . . "ingerid.reinertsen@rohub.com" . "Ingerid Reinertsen" . . "ole.solheim@rohub.com" . "Ole Solheim" . . . "2026-03-03T16:17:28.369+01:00"^^ . . . . "Glioblastoma Segmentation: Comparison of Three Different Software Packages" . 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