@prefix biolink: <
https://w3id.org/biolink/vocab/
> .
@prefix dcterms: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://purl.org/np/RALg4jr1hCvhR9N7uzAeV4OnRh280a0qIlnqMF0ZopDPc
> .
@prefix sub: <
http://purl.org/np/RALg4jr1hCvhR9N7uzAeV4OnRh280a0qIlnqMF0ZopDPc#
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix nt: <
https://w3id.org/np/o/ntemplate/
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix nkg: <
https://w3id.org/um/neurodkg/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/MONDO_0013600
>
biolink:category
biolink:Disease
.
sub:association
rdf:object
<
http://purl.obolibrary.org/obo/MONDO_0013600
> ;
rdf:predicate
biolink:treats
;
rdf:subject
<
https://go.drugbank.com/drugs/DB00980
> ;
a
rdf:Statement
;
rdfs:label
"Ramelteon is a synthetic melatonin receptor agonist with high affinity for the MT1 and MT2 receptors, and is approved by the FDA for use in adults. Only few case reports have been published in children with NDDs reporting in general limited efficacy on night awakenings" ;
biolink:association_type
biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
biolink:has_population_context
sub:cohort
;
biolink:provided_by
<
https://w3id.org/um/NeuroDKG
> ;
biolink:publications
<
https://pubmed.ncbi.nlm.nih.gov/28921528/
> ;
biolink:relation
nkg:OffLabelIndication
.
sub:cohort
rdfs:label
"Children" ;
biolink:category
biolink:Cohort
;
biolink:has_phenotype
<
http://purl.obolibrary.org/obo/MONDO_0100038
> .
<
https://go.drugbank.com/drugs/DB00980
>
biolink:category
biolink:Drug
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-7641-6446
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB" ;
npx:hasSignature
"JgxMRWedTOozzP8ZSOKUKZqbwJjQmjkbhdk/7KNBz524L2GvPFt2UPqhcePuduTeF5H1JrSKNPtVZ/NWGdddtTgv/wIGlERUo78wFHbLHqmJYxPdmZe7IYcQydUFle6k7x0IcV24+ttS8vIx+gtZi3kX6DBto+dLN/Kw7KIMDaY=" ;
npx:hasSignatureTarget
this:
.
this:
dcterms:created
"2021-05-19T20:26:01.809+02:00"^^
xsd:dateTime
;
dcterms:creator
orcid:0000-0002-7641-6446
;
nt:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
nt:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
nt:wasCreatedFromTemplate
<
http://purl.org/np/RAZdZj78B6nKrP1Q00oFzsK07u7WdiY3sToz-H-H2nSgg
> .
}