@prefix biolink: <
https://w3id.org/biolink/vocab/
> .
@prefix dcterms: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://purl.org/np/RAM8XybF7aWxN3kCWJ91nyMTYChDOz0LPKkrzXUNltsUk
> .
@prefix sub: <
http://purl.org/np/RAM8XybF7aWxN3kCWJ91nyMTYChDOz0LPKkrzXUNltsUk#
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix nt: <
https://w3id.org/np/o/ntemplate/
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix nkg: <
https://w3id.org/um/neurodkg/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/HP_0000713
>
biolink:category
biolink:Disease
.
sub:association
rdf:object
<
http://purl.obolibrary.org/obo/HP_0000713
> ;
rdf:predicate
biolink:treats
;
rdf:subject
<
https://go.drugbank.com/drugs/DB01043
> ;
a
rdf:Statement
;
rdfs:label
"Nonpharmacological interventions are suggested as first-line treatment, but aren't effective for every patient, resulting in pharmacological interventions for some patients, consisting of off-label use of antipsychotics, sedative/hypnotics, anxiolytics, acetylcholinesterase inhibitors, memantine, and antidepressants; where efficacy doesn't necessarily outweigh associated risks." ;
biolink:association_type
biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
biolink:has_population_context
sub:cohort
;
biolink:provided_by
<
https://w3id.org/um/NeuroDKG
> ;
biolink:publications
<
https://pubmed.ncbi.nlm.nih.gov/28300462/
> ;
biolink:relation
nkg:OffLabelIndication
.
sub:cohort
rdfs:label
"Elderly" ;
biolink:category
biolink:Cohort
;
biolink:has_phenotype
<
http://purl.obolibrary.org/obo/MONDO_0004975
> .
<
https://go.drugbank.com/drugs/DB01043
>
biolink:category
biolink:Drug
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-7641-6446
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB" ;
npx:hasSignature
"SFsrVpqT11LZ5z8Bj2dU6Vt7FuUHzfFHrKQmCauXbFF9QBt3FRkadcApxY83Qdg3RD9Nb15ywuELS1NB/HryuGrWnqqvUZtS8wXSL4crbH7XvP3ZwpN3JRq7og6YTynCNU+rwDDPdhHqMe2li2joRVEHSeTsybsDjcbfDTuCCd8=" ;
npx:hasSignatureTarget
this:
.
this:
dcterms:created
"2021-05-28T17:19:55.499+02:00"^^
xsd:dateTime
;
dcterms:creator
orcid:0000-0002-7641-6446
;
nt:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
nt:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
nt:wasCreatedFromTemplate
<
http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs
> .
}