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[The human ovarian carcinoma SK-OV-3 cells implanted intraperitoneally (i.p.) in immunodeficient Rag2?/?;Il2rg?/? mice gave rise to a progressive peritoneal carcinomatosis which mimics the fatal condition in advanced human patients.I.p. administration of R-LM249 strongly inhibited carcinomatosis, resulting in 60% of mice free from peritoneal diffusion, and 95% reduction in the total weight of neoplastic nodules.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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