sub:assertion {
ncit:C15675 rdfs:label "Adjuvant Therapy, any therapy that is administered to augment or stimulate other treatment modalities or to minimize or prevent disease recurrence subsequent to the main treatment plan. " .
sub:assertion a nt:AssertionTemplate ;
rdfs:label "Defining a drug indication with its context (BioLink model)" ;
nt:hasStatement sub:st00 ,
sub:st01 ,
sub:st02 ,
sub:st03 ,
sub:st04 ,
sub:st05 ,
sub:st06 ,
sub:st07 ,
sub:st08 ,
sub:st09 ,
sub:st10 ,
sub:st11 ,
sub:st12 ,
sub:st13 ,
sub:st14 .
sub:association a nt:LocalResource ;
rdfs:label "this association" .
sub:associationRelation a nt:GuidedChoicePlaceholder ;
rdfs:label "provide the type of drug indication" ;
nt:possibleValue ncit:C15675 ,
schema:ApprovedIndication ,
schema:PreventionIndication ,
schema:TreatmentIndication ,
nkg:OffLabelIndication ,
nkg:SymptomaticReliefIndication .
sub:cohort a nt:LocalResource ;
rdfs:label "the study cohort" .
sub:cohortAgeLabel a nt:LiteralPlaceholder ;
rdfs:label "describe the life stage or age of the cohort (e.g. Adults)" .
sub:cohortAgeMax a nt:LiteralPlaceholder ;
rdfs:label "describe the maximum age of the cohort (e.g. 80)" .
sub:cohortAgeMin a nt:LiteralPlaceholder ;
rdfs:label "describe the minimum age of the cohort (e.g. 7)" .
sub:hasPhenotype a nt:GuidedChoicePlaceholder ;
rdfs:label "provide additional phenotypes for the cohort" ;
nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
sub:object a nt:GuidedChoicePlaceholder ;
rdfs:label "search for the disease it treats" ;
nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
sub:publication a nt:UriPlaceholder ;
rdfs:label "add the URL of a publication supporting this association (doi, PubMed...)" .
sub:readableassertion a nt:LiteralPlaceholder ;
rdfs:label "describe the assertion concisely (e.g. tylenol treats pain in adults patients)" .
sub:st00 rdf:object sub:readableassertion ;
rdf:predicate rdfs:label ;
rdf:subject sub:association ;
a rdf:Statement ;
nt:statementOrder 0 .
sub:st01 rdf:object sub:subject ;
rdf:predicate rdf:subject ;
rdf:subject sub:association ;
a rdf:Statement ;
nt:statementOrder 1 .
sub:st02 rdf:object sub:object ;
rdf:predicate rdf:object ;
rdf:subject sub:association ;
a rdf:Statement ;
nt:statementOrder 3 .
sub:st03 rdf:object biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
rdf:predicate biolink:association_type ;
rdf:subject sub:association ;
a rdf:Statement ;
nt:statementOrder 19 .
sub:st04 rdf:object sub:associationRelation ;
rdf:predicate biolink:relation ;
rdf:subject sub:association ;
a rdf:Statement ;
nt:statementOrder 6 .
sub:st05 rdf:object <
https://w3id.org/um/NeuroDKG> ;
rdf:predicate biolink:provided_by ;
rdf:subject sub:association ;
a rdf:Statement ;
nt:statementOrder 22 .
sub:st06 rdf:object sub:publication ;
rdf:predicate biolink:publications ;
rdf:subject sub:association ;
a nt:OptionalStatement ;
nt:statementOrder 10 .
sub:st07 a nt:GroupedStatement ,
nt:OptionalStatement ;
nt:hasStatement sub:st07a ,
sub:st07b ,
sub:st07c ;
nt:statementOrder 11 .
sub:st07a rdf:object sub:cohort ;
rdf:predicate biolink:has_population_context ;
rdf:subject sub:association ;
a rdf:Statement ;
nt:statementOrder 12 .
sub:st07b rdf:object sub:cohortAgeLabel ;
rdf:predicate rdfs:label ;
rdf:subject sub:cohort ;
a rdf:Statement ;
nt:statementOrder 13 .
sub:st07c rdf:object biolink:Cohort ;
rdf:predicate biolink:category ;
rdf:subject sub:cohort ;
a rdf:Statement ;
nt:statementOrder 14 .
sub:st08 rdf:object sub:cohortAgeMin ;
rdf:predicate schema:requiredMinAge ;
rdf:subject sub:cohort ;
a nt:OptionalStatement ;
nt:statementOrder 15 .
sub:st09 rdf:object sub:cohortAgeMax ;
rdf:predicate schema:requiredMaxAge ;
rdf:subject sub:cohort ;
a nt:OptionalStatement ;
nt:statementOrder 16 .
sub:st10 rdf:object sub:hasPhenotype ;
rdf:predicate biolink:has_phenotype ;
rdf:subject sub:cohort ;
a nt:OptionalStatement ,
nt:RepeatableStatement ;
nt:statementOrder 18 .
sub:st11 rdf:object rdf:Statement ;
rdf:predicate rdf:type ;
rdf:subject sub:association ;
a rdf:Statement ;
nt:statementOrder 20 .
sub:st12 rdf:object biolink:Drug ;
rdf:predicate biolink:category ;
rdf:subject sub:subject ;
a rdf:Statement ;
nt:statementOrder 23 .
sub:st13 rdf:object biolink:Disease ;
rdf:predicate biolink:category ;
rdf:subject sub:object ;
a rdf:Statement ;
nt:statementOrder 24 .
sub:st14 rdf:object biolink:treats ;
rdf:predicate rdf:predicate ;
rdf:subject sub:association ;
a rdf:Statement ;
nt:statementOrder 21 .
sub:subject a nt:GuidedChoicePlaceholder ;
rdfs:label "search for the indicated drug" ;
nt:possibleValuesFromApi "https://name-resolution-sri.renci.org/lookup?limit=10&string=" .
rdf:Statement rdfs:label "association Statement" .
rdf:object rdfs:label "has disease" .
rdf:predicate rdfs:label "has predicate" .
rdf:subject rdfs:label "has drug" .
rdf:type rdfs:label "has type" .
rdfs:label rdfs:label "has label" .
schema:ApprovedIndication rdfs:label "An indication for a medical therapy that has been formally specified or approved by a regulatory body." .
schema:PreventionIndication rdfs:label "An indication for preventing an underlying condition, symptom, etc." .
schema:TreatmentIndication rdfs:label "An indication for treating an underlying condition." .
schema:requiredMaxAge rdfs:label "participant maximum age is" .
schema:requiredMinAge rdfs:label "participant minimum age is" .
biolink:EvidenceType rdfs:label "EvidenceType" .
biolink:association_type rdfs:label "has BioLink type" .
biolink:category rdfs:label "is a" .
biolink:description rdfs:label "is described by" .
biolink:has_drug rdfs:label "uses drug" .
biolink:has_phenotype rdfs:label "has phenotypes" .
biolink:has_population_context rdfs:label "has population context" .
biolink:id rdfs:label "has id" .
biolink:negated rdfs:label "is negated" .
biolink:provided_by rdfs:label "is provided by" .
biolink:publications rdfs:label "has publications" .
biolink:qualifiers rdfs:label "is qualified by" .
biolink:relation rdfs:label "has relation" .
nkg:OffLabelIndication rdfs:label "An indication found in off-label drug uses" .
nkg:SymptomaticReliefIndication rdfs:label "An indication for only managing the symptoms of the condition" .
}