Nanopublications

@prefix this: <http://purl.org/np/RAP1qAgf90r8AUYRvfBh2OOfvh0_8KGRiB4ONH6ZsiW90> .
@prefix sub: <http://purl.org/np/RAP1qAgf90r8AUYRvfBh2OOfvh0_8KGRiB4ONH6ZsiW90#> .
@prefix drugbank: <http://identifiers.org/drugbank/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix mondo: <http://purl.obolibrary.org/obo/MONDO_> .
@prefix pav: <http://purl.org/pav/> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix ntemplate: <https://w3id.org/np/o/ntemplate/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix pmid: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix ncit: <http://purl.obolibrary.org/obo/NCIT_> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubInfo ;
    a np:Nanopublication .
}

sub:assertion {
  drugbank:DB00363 a biolink:Drug ;
    rdfs:label "Clozapine" ;
    biolink:category biolink:Drug .
  mondo:0005258 a biolink:Disease ;
    rdfs:label "autism spectrum disorder" ;
    biolink:category biolink:Disease .
  sub:association rdf:object mondo:0005258 ;
    rdf:predicate biolink:treats ;
    rdf:subject drugbank:DB00363 ;
    a biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    rdfs:label "Clozapine has a more significant impact for the treatment of positive psychotic symptoms as compared to negative symptoms and has been shown to be effective for aggression, suicidal behaviors, obsessive–compulsive disorder, and autism spectrum disorder." ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    biolink:has_population_context sub:context ;
    biolink:publications pmid:31082865 ;
    biolink:relation ncit:C94303 .
  sub:context a biolink:Cohort ;
    rdfs:label "Children and adolescents" ;
    biolink:category biolink:Cohort .
}

sub:provenance {
sub:assertion prov:wasAttributedTo orcid:0000-0002-7641-6446 .
}

sub:pubInfo {
  sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" ;
    npx:hasSignature "jdlQP1eEo7HinNQrM9ZRZrtKiUt6RWPS6PbHSPWMMnDk5QTyzccwuaTXxbFY8TszEj+kYEHMxTmJ9j6Lq8yIHfAzAhkUAbC1/ZMfbe/mCkxr8Dga/ailvO6JENx/qS2ESAg4v2OlFwd4TsR4gB70g0GTOpNBXEGb/Yk9WoQMXMw=" ;
    npx:hasSignatureTarget this: .
  this: prov:generatedAtTime "2022-09-16T11:50:57.251324"^^xsd:dateTime ;
    prov:wasAttributedTo orcid:0000-0002-1501-1082 ;
    ntemplate:wasCreatedFromTemplate <http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY> .
  biolink: pav:version "2.3.0" .
}