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[To determine if epilepsy-related changes reflect those in another neurological condition, analogous tissue samples harvested from 10 autopsy-verified Alzheimer brains, and from 10 neurologically and neuropathologically normal control patients were analyzed using immunofluorescence histochemistry, western immunoblot, and real-time PCR to determine genotype effects on neuronal number and size, neuronal and glial expressions of amyloid ? (A?) precursor protein (?APP), A?, apolipoprotein E (ApoE), S100B, interleukin-1? and ?, and ? and ? secretases; and on markers of neuronal stress, including DNA/RNA damage and caspase 3 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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