@prefix this: <http://purl.org/np/RAQ8fg2iRzg06A6ge9_ROBUIqNs6AeV83iB-P6wgZFU44> .
@prefix sub: <http://purl.org/np/RAQ8fg2iRzg06A6ge9_ROBUIqNs6AeV83iB-P6wgZFU44#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix pav: <http://purl.org/pav/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix infores: <https://w3id.org/biolink/infores/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix umls: <http://identifiers.org/umls/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubInfo ;
    a np:Nanopublication .
}
sub:assertion {
  <http://identifiers.org/pubchem.compound/4170> a biolink:ChemicalEntity ;
    rdfs:label "Metolazone" ;
    biolink:category biolink:ChemicalEntity .
  umls:C0040524 a biolink:DiseaseOrPhenotypicFeature ;
    rdfs:label "toxemia" ;
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  <http://purl.obolibrary.org/obo/HP_0000969> a biolink:DiseaseOrPhenotypicFeature ;
    rdfs:label "edema" ;
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  <http://purl.obolibrary.org/obo/MONDO_0005044> a biolink:DiseaseOrPhenotypicFeature ;
    rdfs:label "hypertension" ;
    biolink:category biolink:DiseaseOrPhenotypicFeature .
  sub:_1 rdf:object umls:C0040524 ;
    rdf:predicate biolink:treats ;
    rdf:subject <http://identifiers.org/pubchem.compound/4170> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=dd432c13-389e-46b3-8891-0cf1a58800ff> .
  sub:_2 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005044> ;
    rdf:predicate biolink:treats ;
    rdf:subject <file:///app/MyKROX> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=dd432c13-389e-46b3-8891-0cf1a58800ff> .
  sub:_3 rdf:object <http://purl.obolibrary.org/obo/MONDO_0005044> ;
    rdf:predicate biolink:treats ;
    rdf:subject <http://identifiers.org/pubchem.compound/4170> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=dd432c13-389e-46b3-8891-0cf1a58800ff> .
  sub:_4 rdf:object umls:C0040524 ;
    rdf:predicate biolink:treats ;
    rdf:subject <http://identifiers.org/pubchem.compound/4170> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=dd432c13-389e-46b3-8891-0cf1a58800ff> .
  sub:_5 rdf:object <http://purl.obolibrary.org/obo/HP_0000969> ;
    rdf:predicate biolink:treats ;
    rdf:subject <http://identifiers.org/pubchem.compound/4170> ;
    a biolink:Association ;
    biolink:aggregator_knowledge_source infores:knowledge-collaboratory ;
    biolink:category biolink:Association ;
    biolink:publications <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=dd432c13-389e-46b3-8891-0cf1a58800ff> .
}
sub:provenance {
  sub:assertion prov:generatedAtTime "2022-10-11T10:36:46.538990"^^xsd:dateTime ;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 ;
    prov:wasQuotedFrom " Metolazone tablets, USP, are indicated in pregnancy when edema is due to pathologic causes, just as it is in the absence of pregnancy. Diuretics do not prevent development of toxemia of pregnancy, and there is no evidence that they are useful in the treatment of developed toxemia. MyKROX Tablets, a more rapidly available form, are intended for new patients with mild to moderate hypertension." .
  biolink: pav:version "2.3.0" .
}
sub:pubInfo {
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    npx:hasSignatureTarget this: .
  this: prov:generatedAtTime "2022-10-11T10:36:46.538990"^^xsd:dateTime ;
    prov:wasAttributedTo orcid:0000-0002-3668-2627 .
}