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[Dysregulation of ?-catenin and the transcriptional activator FOXM1 mediate oncogenesis, but it is not clear how these proteins become dysregulated in tumors that do not typically carry mutations in adenomatous polyposis coli (APC) or ?-catenin, such as pancreatic ductal adenocarcinomas (PDACs).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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