@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_head {
  this: np:hasAssertion dgn-np:NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_assertion;
    np:hasProvenance dgn-np:NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_provenance;
    np:hasPublicationInfo dgn-np:NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_publicationInfo;
    a np:Nanopublication .
  
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  dgn-np:NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_provenance a np:Provenance .
  
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dgn-np:NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_assertion {
  miriam-gene:102 a ncit:C16612 .
  
  lld:C0010068 a ncit:C7057 .
  
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dgn-np:NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_provenance {
  dgn-np:NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_assertion dcterms:description
      "[Our main findings were: (i) patients with stable (n = 40) and unstable (n = 40) angina had elevated plasma levels of CXCL16 compared with controls (n = 20); (ii) low-dose simvastatin (20 mg qd, n = 15) and high-dose atorvastatin (80 mg qd, n = 9) down-regulated plasma levels of CXCL16 during 6 months of therapy; (iii) in vitro, atorvastatin significantly decreased the interleukin (IL)-1beta-mediated release of CXCL16 from PBMC and endothelial cells; (iv) attenuating effect of atorvastatin on the IL-1beta-mediated release of CXCL16 in PBMC seems to involve post-transcriptional modulation as well as down-regulation of CXCL16 release through inhibition of the protease a disintegrin and metalloproteinase 10 (ADAM10); (v) soluble CXCL16 increased the release of IL-8, monocyte chemoattractant peptide 1, and matrix metalloproteinases in vascular SMC and increased the release of IL-8 and monocyte chemoattractant peptide 1 in PBMC, with particularly enhancing effects in cells from CAD patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
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  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP174789.RATOYvOqYonqKWhYsnAGZwmdB2Vx2xCfQXaAMuvW-DjMQ130_publicationInfo {
  this: dcterms:created "2014-10-02T12:33:34+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
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    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
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