@prefix biolink: <
https://w3id.org/biolink/vocab/
> .
@prefix dcterms: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://purl.org/np/RAU-jWAqmoSJBdswIneCuFj-IOCvLnvmZJyK-_H3WgY9Y
> .
@prefix sub: <
http://purl.org/np/RAU-jWAqmoSJBdswIneCuFj-IOCvLnvmZJyK-_H3WgY9Y#
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix nt: <
https://w3id.org/np/o/ntemplate/
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix nkg: <
https://w3id.org/um/neurodkg/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/MONDO_0001156
>
biolink:category
biolink:Disease
.
sub:association
rdf:object
<
http://purl.obolibrary.org/obo/MONDO_0001156
> ;
rdf:predicate
biolink:treats
;
rdf:subject
<
https://go.drugbank.com/drugs/DB01224
> ;
a
rdf:Statement
;
rdfs:label
"Antipsychotics have been found to reduce BPD symptoms including aripiprazole (mean daily dose: 15 mg); ziprasidone (mean daily dose: 20 to 80 mg), olanzapine (mean daily dose: 5 to 9 mg, daily dose range 5 to 20 mg), haloperidol (mean daily dose 5 mg, daily dose range 4 to 16 mg), Quetiapine XL (at a daily dose of 150 mg). The empirically use of antipsychotics in patients with BPD are considered as off-label use." ;
biolink:association_type
biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
biolink:has_population_context
sub:cohort
;
biolink:provided_by
<
https://w3id.org/um/NeuroDKG
> ;
biolink:publications
<
https://pubmed.ncbi.nlm.nih.gov/28825781/
> ;
biolink:relation
nkg:OffLabelIndication
.
sub:cohort
rdfs:label
"Adults" ;
biolink:category
biolink:Cohort
.
<
https://go.drugbank.com/drugs/DB01224
>
biolink:category
biolink:Drug
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-7641-6446
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCamPJb4SzqpLXn//XJ5dlVfzz6QI+RPmiJTLXF/by2JR7sHMKRsCQDFsYMlq8zGHghOIkjRP9dpLZUtZzUcHt3MXiFKEPo8eGzUe9p+JXKFC8xxkJr94z2vq6IdMf71Iu1GH8SeDAKt/DgYO4zNaw8VuXvxnZRewKZSA+u8zWPVwIDAQAB" ;
npx:hasSignature
"Bj6mmhqAZhZ5VWszscaNOprKe/ybwQAiXnRntRSaFa4Olj+ifNWfgKL6avCyUEBqYMK2VqUzQyUFOitr5SaffLJbFq5mqibLsUKp/9Rd6IUxWihmEUowrGcgwDIeuvbvTSQdD1wi5l3U4lcyPVqlLgfUbbIm7oxSSnyYpetLzVE=" ;
npx:hasSignatureTarget
this:
.
this:
dcterms:created
"2021-05-28T22:38:56.660+02:00"^^
xsd:dateTime
;
dcterms:creator
orcid:0000-0002-7641-6446
;
nt:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
nt:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
nt:wasCreatedFromTemplate
<
http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs
> .
}