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[We suggest that AKT2 inhibition abrogates gemcitabine-induced activation of AKT2 and NF-?B, and promotes gemcitabine-induced PUMA upregulation, resulting in chemosensitization of pancreatic tumors to gemcitabine, which is probably an important strategy for the treatment of pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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