@prefix nt: <
https://w3id.org/np/o/ntemplate/
> .
@prefix this: <
http://purl.org/np/RAZcseMVGLjBsI4G_r8pCp0NQCFiepZXqMQ5xaQfQj7ok
> .
@prefix sub: <
http://purl.org/np/RAZcseMVGLjBsI4G_r8pCp0NQCFiepZXqMQ5xaQfQj7ok#
> .
@prefix drugbank: <
http://identifiers.org/drugbank/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix infores: <
https://w3id.org/biolink/infores/
> .
@prefix hp: <
http://purl.obolibrary.org/obo/HP_
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix pmid: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix ncit: <
http://purl.obolibrary.org/obo/NCIT_
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix biolink: <
https://w3id.org/biolink/vocab/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubInfo
;
a
np:Nanopublication
.
}
sub:assertion
{
drugbank:DB00704
a
biolink:Drug
;
rdfs:label
"Naltrexone" ;
biolink:category
biolink:Drug
.
hp:000098
a
biolink:Disease
;
rdfs:label
"pruritus" ;
biolink:category
biolink:Disease
.
sub:association
rdf:object
hp:000098
;
rdf:predicate
biolink:treats
;
rdf:subject
drugbank:DB00704
;
a
biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
rdfs:label
"Off-label use includes treatment of cholestatic pruritus in adults." ;
biolink:aggregator_knowledge_source
infores:knowledge-collaboratory
;
biolink:category
biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
biolink:has_population_context
sub:context
;
biolink:publications
pmid:30521232
;
biolink:relation
ncit:C94303
.
sub:context
a
biolink:Cohort
;
rdfs:label
"Adults" ;
biolink:category
biolink:Cohort
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-7641-6446
.
}
sub:pubInfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" ;
npx:hasSignature
"ckS3r8891sMj2O6qVWunqCDLMvuvZqFLEB+0BFP/vPyuwzdDrwsJH1ETKK+wD32QQqJVys4DWpNm4OeOhCyglqIyMTQy/rARldh9e/SWFSJJsDGuDX4ZTemI6pU3ks7yfJYSCVtxjPTw0PVEEq23eN8kDqDni5C9z1o3sO+i+Gk=" ;
npx:hasSignatureTarget
this:
.
this:
prov:generatedAtTime
"2022-09-16T11:46:37.706545"^^
xsd:dateTime
;
prov:wasAttributedTo
orcid:0000-0002-1501-1082
;
nt:wasCreatedFromTemplate
<
http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY
> .
biolink:
pav:version
"2.3.0" .
}