@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAapknSKaEkcpmLmq5NTRC2L62IEox6U3O_aQVoHXdkLk> .
@prefix sub: <http://purl.org/np/RAapknSKaEkcpmLmq5NTRC2L62IEox6U3O_aQVoHXdkLk#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix orcid: <https://orcid.org/> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix biolink: <https://w3id.org/biolink/vocab/> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  sub:assertion a nt:AssertionTemplate ;
    rdfs:label "Defining a biomedical association with its context" ;
    nt:hasStatement sub:st00 , sub:st01 , sub:st02 , sub:st03 , sub:st04 , sub:st05 , sub:st06 , sub:st07 , sub:st08 , sub:st09 , sub:st10 , sub:st11 , sub:st12 , sub:st13 , sub:st14 , sub:st15 , sub:st16 , sub:st17 , sub:st18 , sub:st19 , sub:st20 , sub:st21 .
  sub:association a nt:LocalResource ;
    rdfs:label "This association" .
  sub:associationType a nt:GuidedChoicePlaceholder ;
    rdfs:label "search for the association class in the BioLink model" ;
    nt:possibleValue biolink:Association , biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation , biolink:ChemicalToGeneAssociation , biolink:ChemicalToPathwayAssociation , biolink:GeneToDiseaseAssociation , biolink:PairwiseGeneToGeneInteraction ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:hasDrug1 a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the drugs used by this target group" ;
    nt:possibleValue sub:object , sub:subject ;
    nt:possibleValuesFromApi "http://robokop.renci.org:2433/lookup?limit=10&string=" .
  sub:hasDrug2 a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the drugs used by this target group" ;
    nt:possibleValuesFromApi "http://robokop.renci.org:2433/lookup?limit=10&string=" .
  sub:hasPhenotype a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide a URI for the specific phenotype of the target group" ;
    nt:possibleValue biolink:LifeStage , biolink:PopulationOfIndividualOrganisms ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:lifeStage a nt:LocalResource ;
    rdfs:label "The group life stage" .
  sub:lifeStageName a nt:LiteralPlaceholder ;
    rdfs:label "describe the life stage or age of the target group" .
  sub:lifeStageType a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the life stage qualifier class" ;
    nt:possibleValue biolink:LifeStage ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:negated a nt:RestrictedChoicePlaceholder ;
    nt:possibleValue xsd:false , xsd:true .
  sub:object a nt:GuidedChoicePlaceholder ;
    rdfs:label "target biomedical entity" ;
    nt:possibleValuesFromApi "http://robokop.renci.org:2433/lookup?limit=10&string=" .
  sub:objectType a nt:GuidedChoicePlaceholder ;
    rdfs:label "search for the object class in the BioLink model" ;
    nt:possibleValue biolink:ChemicalSubstance , biolink:Disease , biolink:Drug , biolink:Gene , biolink:PhenotypicFeature , biolink:Protein ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:providedBy a nt:UriPlaceholder ;
    rdfs:label "add the URI of the dataset or agent providing the associations" .
  sub:publication a nt:UriPlaceholder ;
    rdfs:label "add the URI of a publication supporting this association (doi, PubMed, article URL, etc)" .
  sub:qualifier a nt:LocalResource ;
    rdfs:label "This qualifier" .
  sub:qualifierObject a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the object of this qualifier (e.g. the disease of the model)" ;
    nt:possibleValue sub:object , sub:subject .
  sub:qualifierRelation a nt:GuidedChoicePlaceholder ;
    rdfs:label "search for the qualifier relation in the BioLink model" ;
    nt:possibleValue biolink:decreases_activity_of , biolink:decreases_degradation_of , biolink:increases_activity_of , biolink:increases_degradation_of , biolink:increases_expression_of , biolink:predisposes , biolink:prevents , biolink:treats ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:qualifierSubjectType a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the target group qualifier class" ;
    nt:possibleValue biolink:LifeStage , biolink:PopulationOfIndividualOrganisms ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:qualifierType a nt:GuidedChoicePlaceholder ;
    rdfs:label "provide the qualifier class" ;
    nt:possibleValue biolink:ClinicalModifier , biolink:OrganismalEntityAsAModelOfDiseaseAssociation ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:readableassertion a nt:LiteralPlaceholder ;
    rdfs:label "describe the assertion concisely (e.g. tylenol treats pain in adults patients)" .
  sub:relation a nt:GuidedChoicePlaceholder ;
    rdfs:label "search for the relation in the BioLink model" ;
    nt:possibleValue biolink:affects , biolink:correlated_with , biolink:interacts_with , biolink:treated_by , biolink:treats ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:st00 rdf:object sub:associationType ;
    rdf:predicate rdf:type ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 0 .
  sub:st01 rdf:object sub:readableassertion ;
    rdf:predicate rdfs:label ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 1 .
  sub:st02 rdf:object sub:subject ;
    rdf:predicate biolink:subject ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 2 .
  sub:st03 rdf:object sub:subjectType ;
    rdf:predicate rdf:type ;
    rdf:subject sub:subject ;
    a rdf:Statement ;
    nt:statementOrder 2 .
  sub:st04 rdf:object sub:relation ;
    rdf:predicate biolink:relation ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 3 .
  sub:st05 rdf:object sub:object ;
    rdf:predicate biolink:object ;
    rdf:subject sub:association ;
    a rdf:Statement ;
    nt:statementOrder 4 .
  sub:st06 rdf:object sub:objectType ;
    rdf:predicate rdf:type ;
    rdf:subject sub:object ;
    a rdf:Statement ;
    nt:statementOrder 2 .
  sub:st07 rdf:object sub:negated ;
    rdf:predicate biolink:negated ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 6 .
  sub:st08 rdf:object sub:providedBy ;
    rdf:predicate biolink:provided_by ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 7 .
  sub:st09 rdf:object sub:publication ;
    rdf:predicate biolink:publications ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 8 .
  sub:st10 rdf:object sub:qualifier ;
    rdf:predicate biolink:qualifiers ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 8 .
  sub:st11 rdf:object sub:qualifierType ;
    rdf:predicate rdf:type ;
    rdf:subject sub:qualifier ;
    a nt:OptionalStatement ;
    nt:statementOrder 9 .
  sub:st12 rdf:object sub:targetGroup ;
    rdf:predicate biolink:subject ;
    rdf:subject sub:qualifier ;
    a nt:OptionalStatement ;
    nt:statementOrder 10 .
  sub:st13 rdf:object sub:qualifierSubjectType ;
    rdf:predicate rdf:type ;
    rdf:subject sub:targetGroup ;
    a nt:OptionalStatement ;
    nt:statementOrder 11 .
  sub:st14 rdf:object sub:hasPhenotype ;
    rdf:predicate biolink:has_phenotype ;
    rdf:subject sub:targetGroup ;
    a nt:OptionalStatement ;
    nt:statementOrder 12 .
  sub:st15 rdf:object sub:lifeStage ;
    rdf:predicate biolink:stage_qualifier ;
    rdf:subject sub:association ;
    a nt:OptionalStatement ;
    nt:statementOrder 13 .
  sub:st16 rdf:object sub:lifeStageType ;
    rdf:predicate rdf:type ;
    rdf:subject sub:lifeStage ;
    a nt:OptionalStatement ;
    nt:statementOrder 13 .
  sub:st17 rdf:object sub:lifeStageName ;
    rdf:predicate biolink:name ;
    rdf:subject sub:lifeStage ;
    a nt:OptionalStatement ;
    nt:statementOrder 13 .
  sub:st18 rdf:object sub:qualifierRelation ;
    rdf:predicate biolink:relation ;
    rdf:subject sub:qualifier ;
    a nt:OptionalStatement ;
    nt:statementOrder 14 .
  sub:st19 rdf:object sub:qualifierObject ;
    rdf:predicate biolink:object ;
    rdf:subject sub:qualifier ;
    a nt:OptionalStatement ;
    nt:statementOrder 14 .
  sub:st20 rdf:object sub:hasDrug1 ;
    rdf:predicate biolink:has_drug ;
    rdf:subject sub:qualifier ;
    a nt:OptionalStatement ;
    nt:statementOrder 15 .
  sub:st21 rdf:object sub:hasDrug2 ;
    rdf:predicate biolink:has_drug ;
    rdf:subject sub:qualifier ;
    a nt:OptionalStatement ;
    nt:statementOrder 16 .
  sub:subject a nt:GuidedChoicePlaceholder ;
    rdfs:label "source biomedical entity" ;
    nt:possibleValuesFromApi "http://robokop.renci.org:2433/lookup?limit=10&string=" .
  sub:subjectType a nt:GuidedChoicePlaceholder ;
    rdfs:label "search for the subject class in the BioLink model" ;
    nt:possibleValue biolink:ChemicalSubstance , biolink:Disease , biolink:Drug , biolink:Gene , biolink:PhenotypicFeature , biolink:Protein ;
    nt:possibleValuesFromApi "http://data.bioontology.org/search?pagesize=20&apikey=fd451bec-eacd-4519-b972-90fb6c7007cb&ontologies=BLM&include_properties=true&q=" .
  sub:targetGroup a nt:LocalResource ;
    rdfs:label "This group" .
  rdf:type rdfs:label "is a" .
  rdfs:label rdfs:label "asserts that" .
  xsd:false rdfs:label "false" .
  xsd:true rdfs:label "true" .
  biolink:description rdfs:label "is described by" .
  biolink:has_drug rdfs:label "uses drug" .
  biolink:has_phenotype rdfs:label "has phenotype" .
  biolink:id rdfs:label "has id" .
  biolink:name rdfs:label "is defined as" .
  biolink:negated rdfs:label "is negated" .
  biolink:object rdfs:label "has object" .
  biolink:provided_by rdfs:label "is provided by" .
  biolink:publications rdfs:label "has publications" .
  biolink:qualifiers rdfs:label "is qualified by" .
  biolink:relation rdfs:label "has relation" .
  biolink:stage_qualifier rdfs:label "has life stage qualifier" .
  biolink:subject rdfs:label "has subject" .
}
sub:provenance {
  sub:assertion prov:wasAttributedTo orcid:0000-0003-4727-9435 .
}
sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" ;
    npx:hasSignature "PrKWiWQdqB2LAQZuOgs/p/EOpo1gRvsrhjh2jA9xaxixyuqOEoC7mfiexYMXwnI4l4CMrKoomCi1awrNJqbp7aJzRtvBilHq+k4tvcGsCcMSHLRrdsKiN5BXVeM/m7WVXdGnrMs3jSnUgQt674CoZiP2ft2XxMsCRtjnM+vTfyY=" ;
    npx:hasSignatureTarget this: .
  this: dcterms:created "2020-11-02T10:00:00+01:00"^^xsd:dateTime ;
    dcterms:creator orcid:0000-0003-4727-9435 .
}