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[Transgenic mouse studies are emphasized which verify that genetic forms of TSEs are linked to mutations in the host PrP gene and that the host species barrier to scrapie infection, scrapie incubation time and the distribution of neuropathology, which define scrapie prion isolates ('strains'), are determined by the structure of PrP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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