@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_head {
  this: np:hasAssertion dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_assertion;
    np:hasProvenance dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_provenance;
    np:hasPublicationInfo dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_assertion a np:Assertion .
  
  dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_provenance a np:Provenance .
  
  dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_assertion {
  miriam-gene:102 a ncit:C16612 .
  
  lld:C0002395 a ncit:C7057 .
  
  dgn-gda:DGNb009e58255cafa98113b897078534322 sio:SIO_000628 miriam-gene:102, lld:C0002395;
    a sio:SIO_001121 .
}

dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_provenance {
  dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_assertion dcterms:description
      "[Results from this investigation suggest that the ADAM10 rs514049-rs653765 C-A promoter haplotype is associated with: (1) higher CSF sAPPα levels in cognitively normal controls compared with Alzheimer's disease (AD) patients, (2) higher postmortem brain hippocampus, but not cerebellum, ADAM10 protein levels in subjects with low plaque scores compared with those with high plaque scores, and (3) higher promoter activity for promoter-only reporter constructs compared with promoter 3' untranslated region (3'UTR) constructs in the human neuroblastoma SHSY5Y cell line, but not in HepG2 or U118 cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:22572541;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP264670.RAeES7knal7Clbw9LRd_pvoiF8HO8MtsOK5c-SPxpbXac130_publicationInfo {
  this: dcterms:created "2014-10-02T12:34:28+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}