@prefix nt: <
https://w3id.org/np/o/ntemplate/
> .
@prefix this: <
http://purl.org/np/RAf77Ce34uUIamj_fn4ejO3mVs4PSdA_JWt_aClA94e0k
> .
@prefix sub: <
http://purl.org/np/RAf77Ce34uUIamj_fn4ejO3mVs4PSdA_JWt_aClA94e0k#
> .
@prefix drugbank: <
http://identifiers.org/drugbank/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix mondo: <
http://purl.obolibrary.org/obo/MONDO_
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix infores: <
https://w3id.org/biolink/infores/
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix pmid: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix ncit: <
http://purl.obolibrary.org/obo/NCIT_
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix biolink: <
https://w3id.org/biolink/vocab/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubInfo
;
a
np:Nanopublication
.
}
sub:assertion
{
drugbank:DB01018
a
biolink:Drug
;
rdfs:label
"Guanfacine" ;
biolink:category
biolink:Drug
.
mondo:0007743
a
biolink:Disease
;
rdfs:label
"Attention deficit-hyperactivity disorder" ;
biolink:category
biolink:Disease
.
sub:association
rdf:object
mondo:0007743
;
rdf:predicate
biolink:treats
;
rdf:subject
drugbank:DB01018
;
a
biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
rdfs:label
"Clonidine and guanfacine (immediate and extended release combined) accounted for 42.6% (952/2233) of the off-label prescriptions written for the 3- to 5-year-old age group." ;
biolink:aggregator_knowledge_source
infores:knowledge-collaboratory
;
biolink:category
biolink:ChemicalToDiseaseOrPhenotypicFeatureAssociation
;
biolink:has_population_context
sub:context
;
biolink:publications
pmid:29290742
;
biolink:relation
ncit:C94303
.
sub:context
a
biolink:Cohort
;
rdfs:label
"Children 3 to 5 years" ;
biolink:category
biolink:Cohort
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-7641-6446
.
}
sub:pubInfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCR9fz0fKCdWOWC+pxhkQhEM/ppbdIYe5TLSdj+lJzSlv9mYBaPgrzVezSwwbmhlHBPDZa4/vHycU315BdmUGq+pXllp9+rWFfrb+kBJwhZjpG6BeyyXBsRFz4jmQVxl/ZYHilQTh/XalYzKkEAyTiEMPee4Kz61PaWOKH24CsnOQIDAQAB" ;
npx:hasSignature
"HDoiwqtqw1alWu8iHQZsMQTUZWxQpcTwftulRs+e1la44T0r44N1FP+9JUp3ip650xAg5ezsN3pfPMq6MJcW7Q8cEyKjT2FPV3GCAVHRVJ8+zRbDrgWBo/M2UKQ+QxQUZJi0FNn18S7o1JdP+LRMHanICPK+5qRSjsUdxnGdpoY=" ;
npx:hasSignatureTarget
this:
.
this:
prov:generatedAtTime
"2022-09-16T11:55:42.254783"^^
xsd:dateTime
;
prov:wasAttributedTo
orcid:0000-0002-1501-1082
;
nt:wasCreatedFromTemplate
<
http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY
> .
biolink:
pav:version
"2.3.0" .
}