@prefix biolink: <
https://w3id.org/biolink/vocab/
> .
@prefix ns1: <
https://w3id.org/np/o/ntemplate/
> .
@prefix this: <
http://purl.org/np/RApuVvBVyYxwEqsEEeOEgwJlEREo4ARm20OsT26gs8RMc
> .
@prefix sub: <
http://purl.org/np/RApuVvBVyYxwEqsEEeOEgwJlEREo4ARm20OsT26gs8RMc#
> .
@prefix schema: <
https://schema.org/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix orcid: <
https://orcid.org/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
<
http://purl.obolibrary.org/obo/DOID_2983
>
biolink:category
biolink:Disease
.
sub:association
rdf:object
<
http://purl.obolibrary.org/obo/DOID_2983
> ;
rdf:predicate
biolink:treats
;
rdf:subject
<
https://identifiers.org/drugbank:DB00887
> ;
a
rdf:Statement
;
rdfs:label
"Bumetanide is contraindicated in anuria. Although bumetanide tablets can be used to induce diuresis in renal insufficiency, any marked increase in blood urea nitrogen or creatinine, or the development of oliguria during therapy of patients with progressive renal disease, is an indication for discontinuation of treatment with bumetanide tablets. Bumetanide is also contraindicated in patients in hepatic coma or in states of severe electrolyte depletion until the condition is improved or corrected. Bumetanide is contraindicated in patients hypersensitive to this drug." ;
biolink:provided_by
<
https://w3id.org/um/NeuroDKG
> ;
biolink:relation
schema:MedicalContraindication
.
<
https://identifiers.org/drugbank:DB00887
>
biolink:category
biolink:Drug
.
}
sub:provenance
{
sub:assertion
prov:wasAttributedTo
orcid:0000-0002-1468-3557
.
}
sub:pubinfo
{
sub:sig
npx:hasAlgorithm
"RSA" ;
npx:hasPublicKey
"MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB" ;
npx:hasSignature
"IZumphNKrv/d3Q91ts1dpJjhYaWw2BgaTtDe8r2ccVnhLNLrPY4YffcLBY6B8hg5Y1kC31Porq57Lo2N4qce4KxSXorHiPfZpsjhocLmraM1Rq/t4FvRqm8sTr2q6/LeJN0ldjDqFaYChZAPe+d7aR0a9MjGojbSz9iQ2YjC5ao=" ;
npx:hasSignatureTarget
this:
.
this:
dct:created
"2021-08-23T19:12:45.253+02:00"^^
xsd:dateTime
;
dct:creator
orcid:0000-0002-1468-3557
;
ns1:wasCreatedFromProvenanceTemplate
<
http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM
> ;
ns1:wasCreatedFromPubinfoTemplate
<
http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM
> ;
ns1:wasCreatedFromTemplate
<
http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY
> .
}