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[CTLA4 +49GG genotype was associated to lower TNF-? and IFN-? levels in patients with chronic HBV infection but this association was diminished by haplotype formation with -318C/T alleles, indicating that the influence of CTLA4 -318C/T and +49A/G polymorphisms on the susceptibility and disease progress of chronic HBV infection may not be effectuated by affecting TNF-? and IFN-? secretion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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