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[While the precise mechanism by which PON1 protects against the development of atherosclerosis is unclear, in vitro studies and the results from PON1 knockout and transgenic mice suggest that this protective effect may be attributed to PON1's ability to attenuate the oxidative modification of lipoprotein particles.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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