@prefix dc1: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAqQwatVeCRIwBGuzxb7zXIZuQA81v-9FiKXKrLg9fLi8> .
@prefix sub: <http://purl.org/np/RAqQwatVeCRIwBGuzxb7zXIZuQA81v-9FiKXKrLg9fLi8#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   <http://purl.obolibrary.org/obo/DOID_11400> bl:category bl:Disease .
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_11400> ;
    rdf:predicate bl:treats ;
    rdf:subject <https://identifiers.org/drugbank:DB06211> ;
    a rdf:Statement ;
    rdfs:label "doripenem for injection is a penem antibacterial indicated in the treatment of the following infections caused by designated susceptible bacteria complicated intra abdominal infections 1 1 complicated urinary tract infections including pyelonephritis 1 2 to reduce the development of drug resistant bacteria and maintain the effectiveness of doripenem for injection and other antibacterial drugs doripenem for injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria 1 3 doripenem for injection is indicated as a single agent for the treatment of complicated intra abdominal infections caused by escherichia coli klebsiella pneumoniae pseudomonas aeruginosa bacteroides caccae bacteroides fragilis bacteroides thetaiotaomicron bacteroides uniformis bacteroides vulgatus streptococcus intermedius streptococcus constellatus peptostreptococcus micros doripenem for injection is indicated as a single agent for the treatment of complicated urinary tract infections including pyelonephritis caused by escherichia coli klebsiella pneumoniae proteus mirabilis pseudomonas aeruginosa acinetobacter baumannii to reduce the development of drug resistant bacteria and maintain the effectiveness of doripenem for injection and other antibacterial drugs doripenem for injection should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria when culture and susceptibility information are available they should be considered in selecting and modifying antibacterial therapy in the absence of such data local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy" ;
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation ;
    bl:provided_by <https://w3id.org/um/NeuroDKG> ;
    bl:relation schema:TreatmentIndication .
  <https://identifiers.org/drugbank:DB06211> bl:category bl:Drug .
}
sub:provenance {
   sub:assertion prov:wasAttributedTo orcid:0000-0002-1468-3557 .
}
sub:pubinfo {
   sub:sig npx:hasAlgorithm "RSA" ;
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB" ;
    npx:hasSignature "DrCJKBZvcJIUv7w6l64dLa621Lv6G5r34+x9Wob93zZzkVPLVT94RX/MK77Dp78YG42K1KfIjYQVVpYB7oz09ZFBUk/C76zVLCZPIu7Yf9OeiN46LIEAv+wI1qvhRXe0dAFLSdZETeVI1h6O9pTQ1v4r1alC0G2HiqmIag4jZ2c=" ;
    npx:hasSignatureTarget this: .
  this: dc1:created "2021-06-13T13:04:54.530+02:00"^^xsd:dateTime ;
    dc1:creator orcid:0000-0002-1468-3557 ;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM> ;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM> ;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs> .
}