[ {
  "@graph" : [ {
    "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU",
    "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ],
    "http://www.nanopub.org/nschema#hasAssertion" : [ {
      "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#assertion"
    } ],
    "http://www.nanopub.org/nschema#hasProvenance" : [ {
      "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#provenance"
    } ],
    "http://www.nanopub.org/nschema#hasPublicationInfo" : [ {
      "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#pubinfo"
    } ]
  } ],
  "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#Head"
}, {
  "@graph" : [ {
    "@id" : "http://purl.obolibrary.org/obo/DOID_1787",
    "https://w3id.org/biolink/vocab/category" : [ {
      "@id" : "https://w3id.org/biolink/vocab/Disease"
    } ]
  }, {
    "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#association",
    "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ {
      "@id" : "http://purl.obolibrary.org/obo/DOID_1787"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ {
      "@id" : "https://w3id.org/biolink/vocab/treats"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ {
      "@id" : "https://identifiers.org/drugbank:DB00682"
    } ],
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@value" : "\"Warfarin sodium is contraindicated in:   Pregnancy Warfarin sodium is contraindicated in women who are pregnant except in pregnant women with mechanical heart valves, who are at high risk of thromboembolism [  see    Warnings and Precautions (5.7)    Use in Specific Populations (8.1 see  Use in Specific Populations (8.1) Warfarin sodium is contraindicated in patients with:   Hemorrhagic tendencies or blood dyscrasias Recent or contemplated surgery of the central nervous system or eye, or traumatic surgery resulting in large open surfaces [  see    Warnings and Precautions (5.8) Bleeding tendencies associated with:  - Active ulceration or overt bleeding of the gastrointestinal, genitourinary, or respiratory tract - Central nervous system hemorrhage - Cerebral aneurysms, dissecting aorta - Pericarditis and pericardial effusions - Bacterial endocarditis Threatened abortion, eclampsia, and preeclampsia Unsupervised patients with conditions associated with potential high level of non-compliance Spinal puncture and other diagnostic or therapeutic procedures with potential for uncontrollable bleeding Hypersensitivity to warfarin or to any other components of this product (e.g., anaphylaxis) [  see    Adverse Reactions (6) Major regional or lumbar block anesthesia Malignant hypertension    Pregnancy, except in women with mechanical heart valves. (  4 5.7 8.1  Hemorrhagic tendencies or blood dyscrasias. (  4  Recent or contemplated surgery of the central nervous system (CNS) or eye, or traumatic surgery resulting in large open surfaces. (  4,  5.8)  Bleeding tendencies associated with certain conditions. (  4  Threatened abortion, eclampsia, and preeclampsia. (  4  Unsupervised patients with potential high levels of non-compliance. (  4  Spinal puncture and other diagnostic or therapeutic procedures with potential for uncontrollable bleeding. (  4  Hypersensitivity to warfarin or any component of the product. (  4  Major regional or lumbar block anesthesia. (  4  Malignant hypertension. (  4\""
    } ],
    "https://w3id.org/biolink/vocab/provided_by" : [ {
      "@id" : "https://w3id.org/um/NeuroDKG"
    } ],
    "https://w3id.org/biolink/vocab/relation" : [ {
      "@id" : "https://schema.org/MedicalContraindication"
    } ]
  }, {
    "@id" : "https://identifiers.org/drugbank:DB00682",
    "https://w3id.org/biolink/vocab/category" : [ {
      "@id" : "https://w3id.org/biolink/vocab/Drug"
    } ]
  } ],
  "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#assertion"
}, {
  "@graph" : [ {
    "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#assertion",
    "http://www.w3.org/ns/prov#wasAttributedTo" : [ {
      "@id" : "https://orcid.org/0000-0002-1468-3557"
    } ]
  } ],
  "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#provenance"
}, {
  "@graph" : [ {
    "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU",
    "http://purl.org/dc/terms/created" : [ {
      "@type" : "http://www.w3.org/2001/XMLSchema#dateTime",
      "@value" : "2021-08-23T12:41:53.913+02:00"
    } ],
    "http://purl.org/dc/terms/creator" : [ {
      "@id" : "https://orcid.org/0000-0002-1468-3557"
    } ],
    "https://w3id.org/np/o/ntemplate/wasCreatedFromProvenanceTemplate" : [ {
      "@id" : "http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM"
    } ],
    "https://w3id.org/np/o/ntemplate/wasCreatedFromPubinfoTemplate" : [ {
      "@id" : "http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM"
    } ],
    "https://w3id.org/np/o/ntemplate/wasCreatedFromTemplate" : [ {
      "@id" : "http://purl.org/np/RAhNHZw6Urw_Mccs4qy6Ws3C9CRuaHpQx8AwuApbWkqnY"
    } ]
  }, {
    "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#sig",
    "http://purl.org/nanopub/x/hasAlgorithm" : [ {
      "@value" : "RSA"
    } ],
    "http://purl.org/nanopub/x/hasPublicKey" : [ {
      "@value" : "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB"
    } ],
    "http://purl.org/nanopub/x/hasSignature" : [ {
      "@value" : "I0GtQu+4sOFGNijxYLWQg6PkNm7ooan+fMz8OYNVMBKvG6dS1118Akz4DREhsNBctReFIkKBB7LVIqVycJzapJ/7xCOpLzf8x6dfhRunmcrhu30HpsYWQ7y55IejGjkZtmMTS/oGg/7nC63rAViSQHdJXzOE8sJ/93UYdFrXDLg="
    } ],
    "http://purl.org/nanopub/x/hasSignatureTarget" : [ {
      "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU"
    } ]
  } ],
  "@id" : "http://purl.org/np/RAshatPzeZvix6B6XKefZ5midNGuGW88Zu6mQ-zmnZJuU#pubinfo"
} ]