@prefix dct: <http://purl.org/dc/terms/> .
@prefix orcid: <http://orcid.org/> .
@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_head {
  this: np:hasAssertion dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_assertion;
    np:hasProvenance dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_provenance;
    np:hasPublicationInfo dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_assertion a np:Assertion .
  
  dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_provenance a np:Provenance .
  
  dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_assertion {
  miriam-gene:595 a ncit:C16612 .
  
  lld:C0346300 a ncit:C7057 .
  
  dgn-gda:DGNf552fa5f892bed8314cf29e20b68c1db sio:SIO_000628 miriam-gene:595, lld:C0346300;
    a sio:SIO_001122 .
}

dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_provenance {
  dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_assertion dct:description
      "[No statistical significance was observed between CCND1 AG genotype and tumour grades. While the functional significance of the observed segregation of the CCND1 A/G polymorphism and tumour grade is unclear, our data suggest that CCND1 allele frequencies and genotype distributions show significant differences between tumour grades in sporadic pituitary adenomas. Since CCND1 genotype may be determined by analysis of peripheral blood samples it may provide a useful predictive marker for those tumours likely to show invasive behaviour. This may be clinically useful in indicating which tumours should receive adjunctive treatment (e.g. radiotherapy) immediately after surgical resection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:11698342;
    prov:wasDerivedFrom dgn-void:gad-20130706;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:gad-20130706 pav:importedOn "2013-07-06"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP47291.RAsybeLHenvmCYGfCBaeOnqznVOQNoXE3ir2bqB2JoPq8130_publicationInfo {
  this: dct:created "2014-10-02T12:32:21+02:00"^^xsd:dateTime;
    dct:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dct:rightsHolder dgn-void:IBIGroup;
    dct:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy orcid:0000-0001-5999-6269, orcid:0000-0002-7534-7661, orcid:0000-0002-9383-528X,
      orcid:0000-0003-0169-8159, orcid:0000-0003-1244-7654;
    pav:createdBy orcid:0000-0003-0169-8159;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}