@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix ns1: <http://www.w3.org/ns/prov#> .
@prefix this: <http://purl.org/np/RAv_btA50-cA8NlI336jHBzHi0U_oDol4v2ELJmTpeWCQ> .
@prefix sub: <http://purl.org/np/RAv_btA50-cA8NlI336jHBzHi0U_oDol4v2ELJmTpeWCQ#> .
@prefix schema: <https://schema.org/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix bl: <https://w3id.org/biolink/vocab/> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  <http://purl.obolibrary.org/obo/DOID_10283> bl:category bl:Disease .
  
  sub:association rdf:object <http://purl.obolibrary.org/obo/DOID_10283>;
    rdf:predicate bl:treats;
    rdf:subject <https://identifiers.org/drugbank:DB01248>;
    a rdf:Statement;
    rdfs:label "docetaxel injection is a microtubule inhibitor indicated for breast cancer bc single agent for locally advanced or metastatic bc after chemotherapy failure and with doxorubicin and cyclophosphamide as adjuvant treatment of operable node positive bc 1 1 non small cell lung cancer nsclc single agent for locally advanced or metastatic nsclc after platinum therapy failure and with cisplatin for unresectable locally advanced or metastatic untreated nsclc 1 2 hormone refractory prostate cancer hrpc with prednisone in androgen independent hormone refractory metastatic prostate cancer 1 3 gastric adenocarcinoma gc with cisplatin and fluorouracil for untreated advanced gc including the gastroesophageal junction 1 4 squamous cell carcinoma of the head and neck cancer scchn with cisplatin and fluorouracil for induction treatment of locally advanced scchn 1 5 docetaxel injection is indicated for the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy docetaxel injection in combination with doxorubicin and cyclophosphamide is indicated for the adjuvant treatment of patients with operable node positive breast cancer docetaxel injection as a single agent is indicated for the treatment of patients with locally advanced or metastatic non small cell lung cancer after failure of prior platinum based chemotherapy docetaxel injection in combination with cisplatin is indicated for the treatment of patients with unresectable locally advanced or metastatic non small cell lung cancer who have not previously received chemotherapy for this condition docetaxel injection in combination with prednisone is indicated for the treatment of patients with androgen independent hormone refractory metastatic prostate cancer docetaxel injection in combination with cisplatin and fluorouracil is indicated for the treatment of patients with advanced gastric adenocarcinoma including adenocarcinoma of the gastroesophageal junction who have not received prior chemotherapy for advanced disease docetaxel injection in combination with cisplatin and fluorouracil is indicated for the induction treatment of patients with locally advanced squamous cell carcinoma of the head and neck scchn";
    bl:association_type bl:ChemicalToDiseaseOrPhenotypicFeatureAssociation;
    bl:provided_by <https://w3id.org/um/NeuroDKG>;
    bl:relation schema:TreatmentIndication .
  
  <https://identifiers.org/drugbank:DB01248> bl:category bl:Drug .
}

sub:provenance {
  sub:assertion ns1:wasAttributedTo orcid:0000-0002-1468-3557 .
}

sub:pubinfo {
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCODwZkXojpEKwk7Ldj2oPPfCstvqrcpgCaTLo235K7ht9C7E1GCkLvUuL2b4VWXJTcZx/hxgDauR8hUeYq/lS6tfTL9yFZsnfl+PWYDyz7vv6N+wJVx2LL8bO6ntCjcOzvW2t2WUeF12Sb6b3I6uOYP0N8iQKts1WasY/yEYKAHQIDAQAB";
    npx:hasSignature "Gqh0lXcBuNTl6f2x2vbFJ3Xe3nQouXL2o8bGnOAX85eDp8rX+BI38H2BNTg/hmlJWrcXNdCYqAiMQvY7bJSeen/x+TJe2pW2A+VCm0TekOo1m3UHZwzwVPeBn0nem5TxeLD4mCNKxGmH0nU4m8N5BGKl7Fg092AoPHmhX+G3dTk=";
    npx:hasSignatureTarget this: .
  
  this: dcterms:created "2021-06-27T21:27:32.588+02:00"^^xsd:dateTime;
    dcterms:creator orcid:0000-0002-1468-3557;
    nt:wasCreatedFromProvenanceTemplate <http://purl.org/np/RANwQa4ICWS5SOjw7gp99nBpXBasapwtZF1fIM3H2gYTM>;
    nt:wasCreatedFromPubinfoTemplate <http://purl.org/np/RAA2MfqdBCzmz9yVWjKLXNbyfBNcwsMmOqcNUxkk1maIM>;
    nt:wasCreatedFromTemplate <http://purl.org/np/RAManV5GZI01JKzW_IPcfOXoiFTcZMmsV7qTCLkdzr4Gs> .
}