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[The association found suggests that the -48C/T polymorphism in the PSN1 gene promoter, which is involved in the modulation of amyloid beta load in human AD, is associated with DS. However, the biological role of this polymorphism in DS-related dementia remains unclear and merits further investigation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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