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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAx9rU3d-KVpqPKVAbmI0tBL6UcgtRUsxlwA_xOEdLddw#_6 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAx9rU3d-KVpqPKVAbmI0tBL6UcgtRUsxlwA_xOEdLddw#_5 http://www.w3.org/ns/prov#value Transgenic mice with a 100% increase in the expression of GPX-1 have an increased carcinogenic response to initiation by 7,12-dimethylbenz[a]anthracene followed by promotion with a phorbol acetate. 7,12-dimethylbenz[a]anthracene^Carcinogenesis induced carcinogenesis = % phorbol_carc = Tetradecanoylphorbol acetate^induced carcinogenesis Gpx1^phorbol_carc Over-expression of human Gpx1 can also protect mice against the neurotoxin 6-hydroxydopamine. 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