@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix this: <http://purl.org/np/RAxBBJ2WkonyQNlXfdCAOaCi64J_xqgVGeaLjVQow9M88> .
@prefix sub: <http://purl.org/np/RAxBBJ2WkonyQNlXfdCAOaCi64J_xqgVGeaLjVQow9M88#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  sub:spi a <https://w3id.org/linkflows/superpattern/terms/SuperPatternInstance> ;
    rdfs:label "A regulatory element within the first intron of FTO affects IRX3 and IRX5 expression during early adipogenesis" ;
    <https://w3id.org/linkflows/superpattern/terms/hasContextClass> <http://purl.org/np/RAtsHwzNs36rGrLnoSbGrPD351Qw033Acoe4zmdXhsYlM#early-human-adipogenesis> ;
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    <https://w3id.org/linkflows/superpattern/terms/hasQualifier> <https://w3id.org/linkflows/superpattern/terms/generallyQualifier> ;
    <https://w3id.org/linkflows/superpattern/terms/hasRelation> <https://w3id.org/linkflows/superpattern/terms/affects> ;
    <https://w3id.org/linkflows/superpattern/terms/hasSubjectClass> <http://purl.org/np/RAxLYvJ1JrRf2JAowYGbGJleQPmqtpXnXsIvse7GmLeT8#regulatory-element-within-the-first-intron-of-FTO> .
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    prov:used sub:quote , <https://doi.org/10.1056/NEJMoa1502214> ;
    prov:wasAssociatedWith orcid:0000-0003-2432-4125 .
  sub:assertion prov:wasGeneratedBy sub:activity .
  sub:quote prov:value "The rs1421085 T-to-C single-nucleotide variant disrupts a conserved motif for the ARID5B repressor, which leads to derepression of a potent preadipocyte enhancer and a doubling of IRX3 and IRX5 expression during early adipocyte differentiation." ;
    prov:wasQuotedFrom <https://doi.org/10.1056/NEJMoa1502214> .
}
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    npx:hasSignatureTarget this: .
  this: dcterms:created "2021-10-27T10:22:03.671-07:00"^^xsd:dateTime ;
    dcterms:creator orcid:0000-0003-2432-4125 ;
    npx:introduces sub:spi ;
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}